SCHEMBL377609

SCHEMBL377609

O=C(O)C[C@@H](C(=O)O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.61
ALDH1A1 P00352 2/20 0.61
GAA P10253 1/20 0.61
POLB P06746 2/20 0.59
TDP1 Q9NUW8 1/20 0.59
CYP2C19 P33261 2/20 0.57
GABBR2 O75899 1/20 0.53
GABBR1 Q9UBS5 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
CYP1A2 P05177 1/20 0.51
TSHR P16473 1/20 0.51
CYP2D6 P10635 1/20 0.50
SRC P12931 1/20 0.50
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
CPA1 P15085 2/20 0.48
CPB1 P15086 1/20 0.48
CPA3 P15088 1/20 0.48
CPB2 Q96IY4 1/20 0.48
LMNA P02545 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29903902 1.00 L3MBTL1 (0.61) L3MBTL1ALDH1A1GAAPOLBTDP1
SCHEMBL377175 1.00 L3MBTL1 (0.61) L3MBTL1ALDH1A1GAAPOLBTDP1
SCHEMBL146867 1.00 L3MBTL1 (0.61) L3MBTL1ALDH1A1GAAPOLBTDP1
SCHEMBL23782080 0.98 L3MBTL1 (0.59) L3MBTL1ALDH1A1GAAPOLBTDP1
SCHEMBL6739142 0.98 L3MBTL1 (0.59) L3MBTL1ALDH1A1GAAPOLBTDP1
SCHEMBL11137284 0.91 L3MBTL1 (0.71) L3MBTL1ALDH1A1GAAPOLBTDP1
SCHEMBL3274728 0.89 ALDH1A1 (0.51) L3MBTL1ALDH1A1GAAPOLBTDP1
SCHEMBL28306756 0.88 L3MBTL1 (0.59) L3MBTL1ALDH1A1GAAPOLBTDP1
SCHEMBL10717750 0.87 MEN1 (0.54) L3MBTL1ALDH1A1GAAPOLBTDP1
SCHEMBL9736992 0.86 GABBR2 (0.53) L3MBTL1ALDH1A1GAAPOLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119351080-A Chiral identification material and preparation method and application thereof 中国科学院化学研究所 2025-01-24 CN claimed
EP-0828767-B1 MOLECULARLY IMPRINTED BEADED POLYMERS AND STABILIZED SUSPENSION POLYMERIZATION OF THE SAME IN PERFLUOROCARBON LIQUIDS IGEN INC (US) 2003-07-30 EP claimed
US-5872198-A MOLECULARLY IMPRINTED POLYMER SUPPORTS CAPABLE OF SEPARATING OR RESOLVING AMINO-ACIDS, AMINO-ACID DERIVATIVES, PHARMACEUTICAL COMPOUNDS AND POLYSACCHARIDES MOSBACH KLAUS (SE) 1999-02-16 US claimed
EP-0828767-A1 MOLECULARLY IMPRINTED BEADED POLYMERS AND STABILIZED SUSPENSION POLYMERIZATION OF THE SAME IN PERFLUOROCARBON LIQUIDS IGEN, INC. (US) 1998-03-18 EP claimed
WO-1996037527-A1 MOLECULARLY IMPRINTED BEADED POLYMERS AND STABILIZED SUSPENSION POLYMERIZATION OF THE SAME IN PERFLUOROCARBON LIQUIDS IGEN, INC. (US) 1996-11-28 WO claimed
US-20260125390-A1 SOLID FORMS OF MACROCYCLIC COMPOUNDS, SALTS AND FORMULATIONS THEREOF, AND METHODS OF PREPARING AND USING THE SAME KURA ONCOLOGY INC (US) 2026-05-07 US disclosed
EP-4720073-A1 SOLID FORMS OF A MACROCYCLIC FARNESYLTRANSFERASE INHIBITOR AND FORMULATIONS THEREOF, AND METHODS OF PREPARING AND USING THE MACROCYCLIC COMPOUND AND ITS SOLID FORMS Kura Oncology, Inc. (US) 2026-04-08 EP disclosed
US-12466835-B1 Solid forms of macrocyclic compounds, salts and formulations thereof, and methods of preparing and using the same KURA ONCOLOGY, INC. (US) 2025-11-11 US disclosed
US-12384757-B2 Methods of synthesizing substituted pyridinone-pyridinyl compounds ACLARIS THERAPEUTICS, INC. (US) 2025-08-12 US disclosed
US-20250195495-A1 RNA Virus Inhibitor Compounds and Uses Thereof THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2025-06-19 US disclosed
CN-119351080-A Chiral identification material and preparation method and application thereof 中国科学院化学研究所 2025-01-24 CN disclosed
US-12186309-B2 RNA virus inhibitor compounds and uses thereof THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2025-01-07 US disclosed
WO-1999064044-A1 NOVEL THERAPEUTIC AGENTS THAT MODULATE 5-HT RECEPTORS ADVANCED MEDICINE, INC. (US) 1999-12-16 WO disclosed
US-5959050-A COMPRISING SPHERICAL, UNIFORMLY SHAPED, AND NON-AGGREGATED PARTICLES FORMED BY SUSPENSION POLYMERIZATION OF TWO DISTINCT ACRYLIC MONOMERS IN THE PRESENCE OF IMPRINT MOLECULE, LIQUID FLUROCARBON, FLUOROCARBON POLYMER MOSBACH, KLAUS (CH) 1999-09-28 US disclosed
US-5872198-A MOLECULARLY IMPRINTED POLYMER SUPPORTS CAPABLE OF SEPARATING OR RESOLVING AMINO-ACIDS, AMINO-ACID DERIVATIVES, PHARMACEUTICAL COMPOUNDS AND POLYSACCHARIDES MOSBACH KLAUS (SE) 1999-02-16 US disclosed
US-5821311-A Stabilizers, polymers, and emulsions useful for molecular imprinting technology MOSBACH KLAUS (CH) 1998-10-13 US disclosed
EP-0828767-A1 MOLECULARLY IMPRINTED BEADED POLYMERS AND STABILIZED SUSPENSION POLYMERIZATION OF THE SAME IN PERFLUOROCARBON LIQUIDS IGEN, INC. (US) 1998-03-18 EP disclosed
WO-1996037527-A1 MOLECULARLY IMPRINTED BEADED POLYMERS AND STABILIZED SUSPENSION POLYMERIZATION OF THE SAME IN PERFLUOROCARBON LIQUIDS IGEN, INC. (US) 1996-11-28 WO disclosed
WO-1995007260-A1 TETRAHYDROISOQUINOLINES AS ALPHA-2 ANTAGONISTS AND BIOGENIC AMINE UPTAKE INHIBITORS ABBOTT LABORATORIES (US) 1995-03-16 WO disclosed
US-5389638-A Nervous system disorders ABBOTT LABORATORIES (US) 1995-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125390-A1 SOLID FORMS OF MACROCYCLIC COMPOUNDS, SALTS AND FORMULATIONS THEREOF, AND METHODS OF PREPARING AND USING THE SAME FDPS, PCTP, MTTP L3MBTL1 2185/4885ALDH1A1 3778/4885GAA 2995/4885
US-12466835-B1 Solid forms of macrocyclic compounds, salts and formulations thereof, and methods of preparing and using the same FNTA, SF3B1, SF3A1 L3MBTL1 1940/4885ALDH1A1 3388/4885GAA 3779/4885
US-12384757-B2 Methods of synthesizing substituted pyridinone-pyridinyl compounds PIR, PUM1, ZRANB2 L3MBTL1 4649/4885ALDH1A1 873/4885GAA 3570/4885
US-20250195495-A1 RNA Virus Inhibitor Compounds and Uses Thereof NSUN3, EIF2AK2, NSUN2 L3MBTL1 747/4885ALDH1A1 3057/4885GAA 351/4885
US-12186309-B2 RNA virus inhibitor compounds and uses thereof NSUN3, EIF2AK2, NSUN2 L3MBTL1 747/4885ALDH1A1 3057/4885GAA 351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.