SCHEMBL490781

SCHEMBL490781

c1ccc(-c2c3ccccc3c(-c3ccccc3)c3cc(N(c4ccccc4)c4ccc(-n5c6ccccc6c6ccccc65)cc4)ccc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.46
KDM4E B2RXH2 3/20 0.46
ATM Q13315 1/20 0.46
KMT2A Q03164 2/20 0.40
IL1R1 P14778 1/20 0.34
HDAC4 P56524 1/20 0.34
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
PTPN1 P18031 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MAPK8 P45983 1/20 0.31
RCE1 Q9Y256 1/20 0.31
RAC2 P15153 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8406184 0.97 L3MBTL1 (0.44) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL490887 0.97 L3MBTL1 (0.44) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL36208 0.95 KDM4E (0.47) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL17740583 0.95 KDM4E (0.47) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL29358439 0.95 KDM4E (0.47) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL29373262 0.93 L3MBTL1 (0.45) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL282306 0.93 L3MBTL1 (0.45) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL10160955 0.93 TSPO (0.40) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL19296449 0.93 TSPO (0.40) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL8406188 0.92 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10079345-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-09-18 US disclosed
US-20160197278-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197278-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197278-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-07-07 US disclosed
US-9287511-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-03-15 US disclosed
US-9287511-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-03-15 US disclosed
EP-2084123-B1 ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LAB (JP) 2014-08-27 EP disclosed
EP-2084123-B1 ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LAB (JP) 2014-08-27 EP disclosed
US-20130306941-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-11-21 US disclosed
US-20130306941-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-11-21 US disclosed
US-20110062428-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-03-17 US disclosed
US-7842945-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-11-30 US disclosed
US-7842945-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-11-30 US disclosed
US-7842945-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-11-30 US disclosed
EP-2084123-A1 ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-08-05 EP disclosed
US-20080017853-A1 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-01-24 US disclosed
US-20080017853-A1 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-01-24 US disclosed
US-20080017853-A1 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-01-24 US disclosed
WO-2007125934-A1 ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-11-08 WO disclosed
WO-2007125934-A1 ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-11-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10079345-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative XPOT, XPO1, XPO7 L3MBTL1 1207/4885KDM4E 3837/4885ATM 1038/4885
US-20080017853-A1 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative XPOT, XPO1, XPO7 L3MBTL1 1207/4885KDM4E 3837/4885ATM 1038/4885
US-20160197278-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative XPOT, XPO1, XPO7 L3MBTL1 1207/4885KDM4E 3837/4885ATM 1038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.