Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 9/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.33 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4794843 | 0.95 | HPGDS (0.44) | HPGDSABL1PIK3CDPIM1PIK3CB | |
| SCHEMBL3937422 | 0.89 | HPGDS (0.43) | HPGDSABL1S1PR1S1PR3PIK3CD | |
| SCHEMBL3933459 | 0.87 | HPGDS (0.48) | HPGDSABL1S1PR1S1PR3PIK3CD | |
| SCHEMBL4794059 | 0.86 | HPGDS (0.45) | HPGDSABL1PIK3CDPIM1PIK3CB | |
| SCHEMBL4794385 | 0.84 | HPGDS (0.45) | HPGDSABL1PIK3CDPIM1PIK3CB | |
| SCHEMBL4780990 | 0.82 | PIP4K2A (0.51) | HPGDSABL1PIK3CDPIM1PIK3CB | |
| SCHEMBL3927726 | 0.82 | HPGDS (0.44) | HPGDSABL1S1PR1S1PR3PIK3CD | |
| SCHEMBL3929384 | 0.81 | HPGDS (0.43) | HPGDSABL1S1PR1S1PR3PIK3CD | |
| SCHEMBL4796842 | 0.81 | HPGDS (0.46) | HPGDSABL1PIK3CDPIM1PIK3CB | |
| SCHEMBL3933604 | 0.81 | HPGDS (0.42) | HPGDSABL1PIK3CDPIM1PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280891-A1 | Anti-cancer agents and uses thereof | LOCUS PHARMACEUTICALS, INC. (US) | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280891-A1 | Anti-cancer agents and uses thereof | NR2E3, RB1, CBR3 | HPGDS 2387/4885ABL1 2221/4885S1PR1 2663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.