Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4906137 | 0.91 | ALDH1A1 (0.37) | TSHRALDH1A1CA12CA14 | |
| SCHEMBL674034 | 0.82 | ALDH1A1 (0.39) | TSHRALDH1A1LMNA | |
| SCHEMBL28870744 | 0.77 | ALDH1A1 (0.43) | TSHRALDH1A1LMNA | |
| SCHEMBL27733003 | 0.75 | ALDH1A1 (0.35) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL16329422 | 0.74 | LMNA (0.41) | TSHRALDH1A1LMNAKMT2ARECQL | |
| SCHEMBL2116492 | 0.70 | TSHR (0.52) | TSHRALDH1A1LMNAGLAPTPRB | |
| SCHEMBL15868617 | 0.68 | ALDH1A1 (0.45) | TSHRALDH1A1 | |
| SCHEMBL27753535 | 0.68 | AKR1B1 (0.40) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL1155285 | 0.68 | TSHR (0.46) | TSHRMEN1KMT2A | |
| SCHEMBL1155720 | 0.68 | TSHR (0.46) | TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080008679-A1 | Osteoinduction-assisting composition | KABUSHIKI KAISHA SHOFU (JP) | 2008-01-10 | — | — | US | disclosed |