Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.30 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4906144 | 0.91 | THRB (0.41) | TSHRCA1CA2THRBALDH1A1 | |
| SCHEMBL610793 | 0.88 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL674035 | 0.83 | THRB (0.42) | TSHRCA1CA2THRBALDH1A1 | |
| SCHEMBL28837643 | 0.82 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8995164 | 0.78 | FOLH1 (0.47) | TSHRTHRBFOLH1 | |
| SCHEMBL75261 | 0.77 | TSHR (0.60) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL27819329 | 0.76 | CA2 (0.67) | TSHRCA1CA2ALDH1A1TDP1 | |
| SCHEMBL18492409 | 0.76 | THRB (0.50) | TSHRCA2THRBALDH1A1POLB | |
| SCHEMBL29011785 | 0.76 | TSHR (0.58) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL883316 | 0.76 | TSHR (0.63) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080008679-A1 | Osteoinduction-assisting composition | KABUSHIKI KAISHA SHOFU (JP) | 2008-01-10 | — | — | US | disclosed |