SCHEMBL4908836

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4914769	0.83	ALDH1A1 (0.55)	ALDH1A1POLBNPC1DGAT2CYP1A2
	SCHEMBL4908766	0.82	ALDH1A1 (0.52)	ALDH1A1POLBNPC1DGAT2LMNA
	SCHEMBL4907748	0.80	SORT1 (0.58)	ALDH1A1POLBNPC1DGAT2SMN1; SMN2
	SCHEMBL4907706	0.79	ALDH1A1 (0.54)	ALDH1A1POLBNPC1DGAT2CYP1A2
	SCHEMBL4914815	0.78	ALDH1A1 (0.53)	ALDH1A1POLBNPC1DGAT2CYP1A2
	SCHEMBL15236978	0.78	POLB (0.65)	ALDH1A1POLBNPC1CYP1A2CYP2C19
	SCHEMBL16455681	0.78	ALDH1A1 (0.55)	ALDH1A1POLBNPC1DGAT2KMT2A
	SCHEMBL4916519	0.78	ALDH1A1 (0.53)	ALDH1A1POLBNPC1DGAT2CYP1A2
	SCHEMBL27335141	0.77	ALDH1A1 (0.59)	ALDH1A1POLBNPC1DGAT2LMNA
	SCHEMBL4914157	0.77	ALDH1A1 (0.57)	ALDH1A1POLBNPC1DGAT2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.