SCHEMBL490884

SCHEMBL490884

O=C(O)CCc1cc(O)ccc1O

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 4/20 0.57
LCK P06239 2/20 0.57
POLB P06746 1/20 0.54
NPSR1 Q6W5P4 1/20 0.50
ALDH1A1 P00352 2/20 0.49
TP53 P04637 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
HPGD P15428 1/20 0.49
ALOX15 P16050 1/20 0.49
ALOX12 P18054 1/20 0.49
CYP2C19 P33261 1/20 0.49
CKS1B P61024 1/20 0.49
SKP2 Q13309 1/20 0.49
HIF1A Q16665 1/20 0.49
HSD17B10 Q99714 1/20 0.49
CHRNA7 P36544 1/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3842422 0.88 EGFR (0.54) EGFRLCKPOLBALDH1A1TP53
SCHEMBL6582394 0.86 F13A1 (0.56) EGFRLCKPOLBALDH1A1TP53
SCHEMBL490491 0.86 POLB (0.67) POLBTYR
SCHEMBL29998634 0.86 POLB (0.67) POLBTYR
SCHEMBL4148828 0.85 F13A1 (0.59) EGFRLCKALDH1A1TP53CYP1A2
SCHEMBL2381980 0.85 F13A1 (0.59) EGFRLCKALDH1A1TP53CYP1A2
SCHEMBL3838231 0.85 F13A1 (0.59) EGFRLCKALDH1A1TP53CYP1A2
SCHEMBL3840098 0.85 F13A1 (0.59) EGFRLCKALDH1A1TP53CYP1A2
SCHEMBL6160355 0.84 IAPP (0.53) EGFRLCKPOLBALDH1A1TP53
SCHEMBL3732327 0.82 POLB (0.46) EGFRLCKPOLBNPSR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5449518-A Bleaching, decoloring skin L'OREAL (FR) 1995-09-12 US claimed
EP-0526302-B1 Depigmentation composition containing derivatives of (2,5-dihydroxyphenyl)-carboxylica OREAL (FR) 1995-03-01 EP claimed
US-4185958-A HAIR DYES BUGAUT ANDREE 1980-01-29 US claimed
US-11866584-B2 High-refractive-index composition, high-refractive-index film, and method for manufacturing high-refractive-index film LG CHEM, LTD. (KR) 2024-01-09 US disclosed
CN-111801388-B High refractive composition, high refractive film, and method for manufacturing high refractive film 株式会社LG化学 2022-04-01 CN disclosed
US-20210095128-A1 HIGH-REFRACTIVE-INDEX COMPOSITION, HIGH-REFRACTIVE-INDEX FILM, AND METHOD FOR MANUFACTURING HIGH-REFRACTIVE-INDEX FILM LG CHEM, LTD. (KR) 2021-04-01 US disclosed
CN-111801388-A High refractive composition, high refractive film, and method for manufacturing high refractive film 株式会社LG化学 2020-10-20 CN disclosed
WO-2020060257-A1 HIGH-REFRACTIVE-INDEX COMPOSITION, HIGH-REFRACTIVE-INDEX FILM, AND METHOD FOR MANUFACTURING HIGH-REFRACTIVE-INDEX FILM 주식회사 엘지화학 2020-03-26 WO disclosed
US-20190211202-A1 ADDUCTS AND USES THEREOF HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2019-07-11 US disclosed
EP-3500627-A1 ADDUCTS AND USES THEREOF Huntsman Advanced Materials Americas LLC (US) 2019-06-26 EP disclosed
EP-2726530-B1 HYBRID EPOXY RESIN ADDUCTS BLUE CUBE IP LLC (US) 2018-09-12 EP disclosed
EP-0469492-A2 Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1992-02-05 EP disclosed
US-4753673-A GRASSY WEEDS THE DOW CHEMICAL COMPANY (US) 1988-06-28 US disclosed
US-4628099-A INTERMEDIATES FOR HERBICIDES THE DOW CHEMICAL COMPANY (US) 1986-12-09 US disclosed
US-4551170-A Herbicidal trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanols and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1985-11-05 US disclosed
US-4523017-A REACTING CHLORIDE SUBSTITUTED PYRIDINE COMPOUND WITH SUBSTITUTED PHENOL COMPOUND THE DOW CHEMICAL COMPANY (US) 1985-06-11 US disclosed
US-4491468-A Herbicidal trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanenitriles and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1985-01-01 US disclosed
US-4479001-A Trifluoromethyl pyridinylthiophenoxy propanoic acids and propanols and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1984-10-23 US disclosed
US-4289495-A HAIR DYES, STORAGE STABILITY L'OREAL (FR) 1981-09-15 US disclosed
US-4236912-A Quinolinyloxyphenoxy and quinolyinylthiophenoxy alkanoic acids and derivatives thereof and methods of herbicidal use THE DOW CHEMICAL COMPANY (US) 1980-12-02 US disclosed