Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | F13A1 | P00488 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582394 | 0.94 | F13A1 (0.56) | EGFRLCKF13A1POLBTYR | |
| SCHEMBL4148828 | 0.93 | F13A1 (0.59) | EGFRLCKF13A1TYRALDH1A1 | |
| SCHEMBL3840098 | 0.93 | F13A1 (0.59) | EGFRLCKF13A1TYRALDH1A1 | |
| SCHEMBL3838231 | 0.93 | F13A1 (0.59) | EGFRLCKF13A1TYRALDH1A1 | |
| SCHEMBL2381980 | 0.93 | F13A1 (0.59) | EGFRLCKF13A1TYRALDH1A1 | |
| SCHEMBL3835233 | 0.90 | F13A1 (0.49) | EGFRLCKF13A1POLBTYR | |
| SCHEMBL8764373 | 0.89 | TYR (0.63) | POLBTYRTP53CYP3A4ALOX15 | |
| SCHEMBL490884 | 0.88 | EGFR (0.57) | EGFRLCKPOLBTYRALDH1A1 | |
| SCHEMBL7794268 | 0.87 | EGFR (0.49) | EGFRLCKTYRALDH1A1TP53 | |
| SCHEMBL8764494 | 0.85 | TYR (0.59) | F13A1POLBTYRTP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449518-A | Bleaching, decoloring skin | L'OREAL (FR) | 1995-09-12 | — | — | US | claimed |
| EP-0526302-B1 | Depigmentation composition containing derivatives of (2,5-dihydroxyphenyl)-carboxylica | OREAL (FR) | 1995-03-01 | — | — | EP | claimed |
| US-8505730-B2 | Compositions, kits and regimens for the treatment of skin, especially décolletage | JR CHEM, LLC (US) | 2013-08-13 | — | — | US | disclosed |
| US-20120312717-A1 | COMPOSITIONS, KITS AND REGIMENS FOR THE TREATMENT OF SKIN, ESPECIALLY DECOLLETAGE | JR CHEM, LLC (US) | 2012-12-13 | — | — | US | disclosed |
| US-8273791-B2 | Compositions, kits and regimens for the treatment of skin, especially décolletage | JR CHEM, LLC (US) | 2012-09-25 | — | — | US | disclosed |
| EP-2087880-A2 | Compositions, kits and regimens for the treatment of skin, especially décolletage | Jr Chem, LLC (US) | 2009-08-12 | — | — | EP | disclosed |
| US-20090176876-A1 | COMPOSITIONS, KITS AND REGIMENS FOR THE TREATMENT OF SKIN, ESPECIALLY DECOLLETAGE | JR CHEM, LLC (US) | 2009-07-09 | — | — | US | disclosed |
| US-6960347-B2 | Composition based on N-cholesteryloxycarbonyl-4-para-aminophenol and hydroquinone or one of its derivatives | L'OREAL (FR) | 2005-11-01 | — | — | US | disclosed |
| US-20010036446-A1 | Composition based on N-cholesteryloxycarbonyl-4-para-aminophenol and hydroquinone or one of its derivatives | L'OREAL (FR) | 2001-11-01 | — | — | US | disclosed |
| US-5667792-A | CARBOXY DERIVATIVES OF HYDROQUINONE AS BLEACHES FOR SKIN | L'OREAL (FR) | 1997-09-16 | — | — | US | disclosed |
| US-5637756-A | TREATMENT OF SKIN DISORDERS, BLEACHING OF PIGMENTED SPOTS, COSMETICS | L'OREAL (FR) | 1997-06-10 | — | — | US | disclosed |
| US-5587173-A | Utilization of derivatives of 2,5 dihydroxyphenyl-carboxylic acid amides and their salts in preparation of a cosmetic or dermatological composition with a depigmenting action | L'OREAL (FR) | 1996-12-24 | — | — | US | disclosed |
| US-5585105-A | Utilization of derivatives of 2,5-dihydroxyphenylcarboxylic acids, their homologs, and their salts in preparation of a cosmetic or dermatological composition with a depigmenting action | L'OREAL (FR) | 1996-12-17 | — | — | US | disclosed |
| EP-0509149-B1 | Thermal dye sublimation transfer receiving element | AGFA GEVAERT NV (BE) | 1996-03-13 | — | — | EP | disclosed |
| US-5449518-A | Bleaching, decoloring skin | L'OREAL (FR) | 1995-09-12 | — | — | US | disclosed |
| US-5284815-A | Image-receiving layer containing an isocyanate-based polymer having a crosslinked and cured surface; dyeability; releasability from the dye donor element | AGFA-GEVAERT, N.V. (BE) | 1994-02-08 | — | — | US | disclosed |
| EP-0509149-A1 | Thermal dye sublimation transfer receiving element | AGFA-GEVAERT N.V. (BE) | 1992-10-21 | — | — | EP | disclosed |
| US-4168980-A | SILVER IMIDAZOLINE-2-THIONE | EASTMAN KODAK COMPANY (US) | 1979-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176876-A1 | COMPOSITIONS, KITS AND REGIMENS FOR THE TREATMENT OF SKIN, ESPECIALLY DECOLLETAGE | RARG, RARA, RXRG | EGFR 1252/4885LCK 2747/4885F13A1 868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.