Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 17/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.57 |
| ▸ | CCR4 | P51679 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CCR5 | P51681 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14006443 | 0.95 | CCR2 (0.71) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL14006403 | 0.84 | CCR2 (0.75) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL4913268 | 0.84 | CCR2 (0.75) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| Trifluoroacetic Acid SCHEMBL4909946 | 0.84 | CCR2 (0.69) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| Trifluoroacetic Acid SCHEMBL4913328 | 0.84 | CCR2 (0.65) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL4910472 | 0.80 | CCR2 (1.00) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL4914005 | 0.79 | CCR2 (0.74) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| Trifluoroacetic Acid SCHEMBL4909953 | 0.79 | CCR2 (0.62) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL4902411 | 0.79 | CCR2 (0.82) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| Trifluoroacetic Acid SCHEMBL4902403 | 0.79 | CCR2 (0.90) | CCR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293720-A1 | Pyridinyl Sulfonamide Modulators of Chemokine Receptors | GLAXO GROUP LIMITED (GB) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293720-A1 | Pyridinyl Sulfonamide Modulators of Chemokine Receptors | CCR2, CCR1, CCRL2 | CCR2 1/4885CYP3A4 1414/4885CYP2C9 1296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.