SCHEMBL490909

SCHEMBL490909

CCOC(=O)CCc1ccc(OC)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.70
CYP4A11 Q02928 1/20 0.70
MAPT P10636 3/20 0.65
LMNA P02545 2/20 0.65
L3MBTL1 Q9Y468 2/20 0.65
F2RL1 P55085 1/20 0.62
GLA P06280 1/20 0.60
KMT2A Q03164 1/20 0.60
ALDH1A1 P00352 3/20 0.58
TDP1 Q9NUW8 2/20 0.58
ALOX5 P09917 1/20 0.55
PKM P14618 1/20 0.55
CYP4Z1 Q86W10 1/20 0.55
POLB P06746 1/20 0.54
NFKB1 P19838 1/20 0.54
NFKB2 Q00653 1/20 0.54
RELA Q04206 1/20 0.54
FFAR1 O14842 1/20 0.54
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10736550 0.95 CYP4F2 (0.64) CYP4F2CYP4A11MAPTLMNAL3MBTL1
SCHEMBL432816 0.95 CYP4F2 (0.64) CYP4F2CYP4A11MAPTLMNAL3MBTL1
SCHEMBL1239542 0.90 ALOX5 (0.65) CYP4F2CYP4A11MAPTLMNAL3MBTL1
SCHEMBL68902 0.89 CYP4F2 (0.85) CYP4F2CYP4A11MAPTLMNAL3MBTL1
SCHEMBL7999711 0.89 ALOX5 (0.59) CYP4F2CYP4A11MAPTLMNAL3MBTL1
SCHEMBL10763604 0.87 F2RL1 (0.73) CYP4F2CYP4A11MAPTLMNAL3MBTL1
SCHEMBL19457413 0.87 MAPT (0.56) CYP4F2CYP4A11MAPTLMNAL3MBTL1
SCHEMBL3675681 0.87 ALOX5 (0.57) CYP4F2CYP4A11MAPTLMNAL3MBTL1
SCHEMBL275760 0.87 F2RL1 (0.58) CYP4F2CYP4A11MAPTLMNAL3MBTL1
SCHEMBL15164347 0.86 F2RL1 (0.62) CYP4F2CYP4A11MAPTLMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12398089-B2 Method for preparing organic carboxylic ester by using combined catalyst of aryl bidentate phosphine ligand NANJING CHENGZHI CLEAN ENERGY CO. LTD. (CN) 2025-08-26 US disclosed
US-20220298097-A1 METHOD FOR PREPARING ORGANIC CARBOXYLIC ESTER BY USING COMBINED CATALYST OF ARYL BIDENTATE PHOSPHINE LIGAND NANJING CHENGZHI CLEAN ENERGY CO. LTD. (CN) 2022-09-22 US disclosed
CN-111087306-B Method for preparing organic carboxylic ester by aryl bidentate phosphine ligand combined catalysis 南京诚志清洁能源有限公司 2021-08-03 CN disclosed
WO-2021129138-A1 METHOD FOR PREPARING ORGANIC CARBOXYLIC ESTER BY MEANS OF COMBINATORIAL CATALYSIS WITH ARYL BIDENTATE PHOSPHINE LIGAND 南京诚志清洁能源有限公司 2021-07-01 WO disclosed
WO-2021129138-A1 METHOD FOR PREPARING ORGANIC CARBOXYLIC ESTER BY MEANS OF COMBINATORIAL CATALYSIS WITH ARYL BIDENTATE PHOSPHINE LIGAND 南京诚志清洁能源有限公司 2021-07-01 WO disclosed
CN-111087306-A Method for preparing organic carboxylic ester by aryl bidentate phosphine ligand combined catalysis 南京诚志清洁能源有限公司 2020-05-01 CN disclosed
CN-108473612-A The manufacturing method of solid catalyst component for olefin polymerization, polymerization of olefines catalyst and olefin polymer 东邦钛株式会社 2018-08-31 CN disclosed
EP-1583738-B1 INDENONCARBOXYLIC ACIDS DERIVATIVES AND THEIR USE FOR THE TREATMENT OF AND PREVENTING DIABETES AND DYSLIPIDAEMIA MERCK PATENT GMBH (DE) 2017-05-10 EP disclosed
US-8772226-B2 Methods and compositions for the detection of cancer THE JOHNS HOPKINS UNIVERSITY (US) 2014-07-08 US disclosed
US-8772226-B2 Methods and compositions for the detection of cancer THE JOHNS HOPKINS UNIVERSITY (US) 2014-07-08 US disclosed
EP-1583738-A1 INDENONCARBOXYLIC ACIDS DERIVATIVES AND THEIR USE FOR THE TREATMENT OF AND PREVENTING DIABETES AND DYSLIPIDAEMIA MERCK PATENT GmbH (DE) 2005-10-12 EP disclosed
WO-2004063148-A1 INDENONCARBOXYLIC ACIDS DERIVATIVES AND THEIR USE FOR THE TREATMENT OF AND PREVENTING DIABETES AND DYSLIPIDAEMIA MERCK PATENT GMBH (DE) 2004-07-29 WO disclosed
EP-0325245-B1 Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use TANABE SEIYAKU CO (JP) 1993-10-20 EP disclosed
US-4948810-A PLATELET AGGREGATION INHIBITORS TANABE SEIYAKU CO., LTD. (JP) 1990-08-14 US disclosed
EP-0325245-A1 Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use TANABE SEIYAKU CO., LTD. (JP) 1989-07-26 EP disclosed
EP-0120304-A2 Substituted 4,10-dihydro-10-oxothieno benzoxepins and intermediates thereof, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1984-10-03 EP disclosed
US-4395410-A Quaternary ammonium antiarrhythmic drugs ELI LILLY AND COMPANY (US) 1983-07-26 US disclosed
EP-0002604-B1 QUATERNARY AMMONIUM SALTS, AND THEIR FORMULATIONS AND PREPARATION ELI LILLY AND COMPANY (US) 1983-05-04 EP disclosed
US-4289787-A PROLONG ACTION POTENTIAL OF CARDIAC TISSUE ELI LILLY AND COMPANY (US) 1981-09-15 US disclosed
EP-0002604-A1 Quaternary ammonium salts, and their formulations and preparation ELI LILLY AND COMPANY (US) 1979-06-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220298097-A1 METHOD FOR PREPARING ORGANIC CARBOXYLIC ESTER BY USING COMBINED CATALYST OF ARYL BIDENTATE PHOSPHINE LIGAND POF1B, ADH1C, OSBP CYP4F2 57/4885CYP4A11 53/4885MAPT 4032/4885
US-12398089-B2 Method for preparing organic carboxylic ester by using combined catalyst of aryl bidentate phosphine ligand POF1B, ADH1C, OSBP CYP4F2 57/4885CYP4A11 53/4885MAPT 4032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.