SCHEMBL490911

SCHEMBL490911

CCOC(=O)CCc1ccc(O)c(O)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.73
IAPP P10997 3/20 0.63
CYP4F2 P78329 1/20 0.63
CYP4A11 Q02928 1/20 0.63
YWHAG P61981 1/20 0.55
CA12 O43570 1/20 0.51
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
CA7 P43166 1/20 0.51
CA9 Q16790 1/20 0.51
CA14 Q9ULX7 1/20 0.51
CYP19A1 P11511 1/20 0.51
TYR P14679 1/20 0.51
CYP4Z1 Q86W10 1/20 0.50
TTR P02766 1/20 0.49
DPP4 P27487 1/20 0.49
KDM4E B2RXH2 1/20 0.49
ALDH1A1 P00352 1/20 0.49
LMNA P02545 1/20 0.49
MAPT P10636 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30291871 1.00 APP (0.73) APPIAPPCYP4F2CYP4A11YWHAG
SCHEMBL16319014 0.89 CYP4F2 (0.61) APPIAPPCYP4F2CYP4A11YWHAG
SCHEMBL8984895 0.89 CYP4F2 (0.61) APPIAPPCYP4F2CYP4A11YWHAG
SCHEMBL1549436 0.89 CYP4F2 (0.61) APPIAPPCYP4F2CYP4A11YWHAG
SCHEMBL2432075 0.87 CYP4F2 (0.59) APPIAPPCYP4F2CYP4A11YWHAG
SCHEMBL3740648 0.86 CYP4F2 (0.58) APPIAPPCYP4F2CYP4A11YWHAG
SCHEMBL5274836 0.86 CYP4F2 (0.58) APPIAPPCYP4F2CYP4A11YWHAG
SCHEMBL9925913 0.86 CYP4F2 (0.58) APPIAPPCYP4F2CYP4A11YWHAG
SCHEMBL27915291 0.86 CYP4F2 (0.58) APPIAPPCYP4F2CYP4A11YWHAG
SCHEMBL3746070 0.86 CYP4F2 (0.58) APPIAPPCYP4F2CYP4A11YWHAG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11673997-B2 Work time to walk-on time ratio by adding a phenolic catalyst to polyaspartic flooring formulations COVESTRO LLC (US) 2023-06-13 US claimed
EP-4004076-A1 IMPROVED WORK TIME TO WALK-ON TIME RATIO BY ADDING A PHENOLIC CATALYST TO POLYASPARTIC FLOORING FORMULATIONS Covestro LLC (US) 2022-06-01 EP claimed
CN-114432506-A Zwitterion functionalized biological material, and preparation method and application thereof 东莞市人民医院 2022-05-06 CN claimed
CN-114144454-A Improved operating time to open-run time ratio by adding phenolic catalysts to polyaspartic flooring formulations 科思创有限公司 2022-03-04 CN claimed
US-20210032407-A1 WORK TIME TO WALK-ON TIME RATIO BY ADDING A PHENOLIC CATALYST TO POLYASPARTIC FLOORING FORMULATIONS COVESTRO LLC 2021-02-04 US claimed
WO-2021021801-A1 IMPROVED WORK TIME TO WALK-ON TIME RATIO BY ADDING A PHENOLIC CATALYST TO POLYASPARTIC FLOORING FORMULATIONS COVESTRO LLC (US) 2021-02-04 WO claimed
US-20100168279-A1 THERMALLY CURABLE EPOXY-AMINE BARRIER SEALANTS HENKEL AG & CO. KGAA (DE) 2010-07-01 US claimed
EP-2001924-A1 THERMALLY CURABLE EPOXY-AMINE BARRIER SEALANTS National Starch and Chemical Investment Holding Corporation (US) 2008-12-17 EP claimed
WO-2007114822-A1 THERMALLY CURABLE EPOXY-AMINE BARRIER SEALANTS NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 2007-10-11 WO claimed
JP-2053767-A None JP disclosed
EP-4526362-A1 EXTENDED WORK TIME POLYASPARTIC FLOOR COATING FORMULATIONS Covestro LLC (US) 2025-03-26 EP disclosed
EP-4321551-A1 EXTENDED WORK TIME POLYASPARTIC FLOOR COATING FORMULATIONS Covestro LLC (US) 2024-02-14 EP disclosed
WO-2023224846-A1 EXTENDED WORK TIME POLYASPARTIC FLOOR COATING FORMULATIONS COVESTRO LLC (US) 2023-11-23 WO disclosed
US-11673997-B2 Work time to walk-on time ratio by adding a phenolic catalyst to polyaspartic flooring formulations COVESTRO LLC (US) 2023-06-13 US disclosed
US-5232923-A Stimulates production of nerve growth factor; administering for treatment of regressive disorders of the central nervous system MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1993-08-03 US disclosed
EP-0495998-A1 DIHYDROCAFFEIC ACID AMIDE DERIVATIVE AND APPLICATION THEREOF AS MEDICINE MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-07-29 EP disclosed
US-5116979-A Alzheimer*s disease; induces secretion of nerve growth factor MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1992-05-26 US disclosed
EP-0418065-A2 Dihydrocaffeic acid derivatives, use thereof for medical treatments and pharmaceutical preparations containing same MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-03-20 EP disclosed
JP-H0253767-A DIHYDROCAFFEIC ACID AMIDE COMPOUND AND REMEDY CONAINING THE SAME AMIDE AS ACTIVE INGREDIENT MITSUI TOATSU CHEM INC 1990-02-22 JP disclosed
EP-0333522-A2 Catechol derivatives and pharmaceutical preparations containing same MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-09-20 EP disclosed