Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.61 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.61 |
| ▸ | APP | P05067 | 2/20 | 0.58 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.49 |
| ▸ | IAPP | P10997 | 3/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.47 |
| ▸ | YWHAG | P61981 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30291871 | 0.89 | APP (0.73) | CYP4F2CYP4A11APPCYP4Z1IAPP | |
| SCHEMBL490911 | 0.89 | APP (0.73) | CYP4F2CYP4A11APPCYP4Z1IAPP | |
| SCHEMBL1549436 | 0.87 | CYP4F2 (0.61) | CYP4F2CYP4A11APPCYP4Z1IAPP | |
| SCHEMBL27972225 | 0.85 | APP (0.51) | CYP4F2CYP4A11APPIAPPALDH1A1 | |
| SCHEMBL5274836 | 0.84 | CYP4F2 (0.58) | CYP4F2CYP4A11APPCYP4Z1IAPP | |
| SCHEMBL27915291 | 0.84 | CYP4F2 (0.58) | CYP4F2CYP4A11APPCYP4Z1IAPP | |
| SCHEMBL9925913 | 0.84 | CYP4F2 (0.58) | CYP4F2CYP4A11APPCYP4Z1IAPP | |
| SCHEMBL3740648 | 0.84 | CYP4F2 (0.58) | CYP4F2CYP4A11APPCYP4Z1IAPP | |
| SCHEMBL8984895 | 0.84 | CYP4F2 (0.61) | CYP4F2CYP4A11APPCYP4Z1IAPP | |
| SCHEMBL1008790 | 0.83 | YWHAG (0.53) | CYP4F2CYP4A11CYP4Z1YWHAGTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181186-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-11-10 | — | — | US | disclosed |
| US-20150045378-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-02-12 | — | — | US | disclosed |
| EP-2816032-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2014-12-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045378-A1 | AROMATIC RING COMPOUND | GPR119, GPR27, GPR4 | CYP4F2 2229/4885CYP4A11 304/4885APP 1420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.