Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.58 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.58 |
| ▸ | APP | P05067 | 2/20 | 0.55 |
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.47 |
| ▸ | IAPP | P10997 | 3/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | YWHAG | P61981 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30291871 | 0.86 | APP (0.73) | CYP4F2CYP4A11APPCYP4Z1IAPP | |
| SCHEMBL490911 | 0.86 | APP (0.73) | CYP4F2CYP4A11APPCYP4Z1IAPP | |
| SCHEMBL16319014 | 0.84 | CYP4F2 (0.61) | CYP4F2CYP4A11APPCYP4Z1IAPP | |
| SCHEMBL3740648 | 0.82 | CYP4F2 (0.58) | CYP4F2CYP4A11APPCYP4Z1IAPP | |
| SCHEMBL5274836 | 0.82 | CYP4F2 (0.58) | CYP4F2CYP4A11APPCYP4Z1IAPP | |
| SCHEMBL27915291 | 0.82 | CYP4F2 (0.58) | CYP4F2CYP4A11APPCYP4Z1IAPP | |
| SCHEMBL1549436 | 0.81 | CYP4F2 (0.61) | CYP4F2CYP4A11APPCYP4Z1IAPP | |
| SCHEMBL8984895 | 0.81 | CYP4F2 (0.61) | CYP4F2CYP4A11APPCYP4Z1IAPP | |
| SCHEMBL491225 | 0.81 | CYP19A1 (0.60) | CYP4F2CYP4A11APPGAAALOX5 | |
| SCHEMBL2432075 | 0.80 | CYP4F2 (0.59) | CYP4F2CYP4A11APPCYP4Z1IAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569892-B1 | CALCILYTIC COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2012-06-13 | — | — | EP | disclosed |