Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PRNP | P04156 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2278000 | 0.75 | PRNP (0.43) | NPSR1KDM4ERAB9AKMT2APRNP | |
| SCHEMBL2280462 | 0.74 | KMT2A (0.49) | SMN1; SMN2L3MBTL1NPSR1ALDH1A1KDM4E | |
| SCHEMBL1061506 | 0.74 | RXFP1 (0.50) | SMN1; SMN2L3MBTL1NPSR1ALDH1A1KDM4E | |
| SCHEMBL4825382 | 0.73 | MC4R (0.38) | SMN1; SMN2MC4RNPSR1ALDH1A1KDM4E | |
| SCHEMBL4823936 | 0.72 | KDM4E (0.47) | SMN1; SMN2MC4RALDH1A1KDM4EKMT2A | |
| SCHEMBL4007811 | 0.71 | KDM4E (0.46) | SMN1; SMN2MC4RALDH1A1KDM4EKMT2A | |
| SCHEMBL18920757 | 0.71 | KDM4E (0.46) | SMN1; SMN2MC4RALDH1A1KDM4EKMT2A | |
| SCHEMBL27004025 | 0.71 | L3MBTL1 (0.56) | SMN1; SMN2L3MBTL1NPSR1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL4823620 | 0.70 | ALDH1A1 (0.45) | SMN1; SMN2MC4RALDH1A1KDM4ERAB9A | |
| SCHEMBL4825375 | 0.69 | SYK (0.40) | SMN1; SMN2MC4RALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269217-A1 | Melanocortin-4 receptor binding compounds and methods of use thereof | ORE PHARMACEUTICALS, INC. (US) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269217-A1 | Melanocortin-4 receptor binding compounds and methods of use thereof | MC4R, MC5R, MC3R | SMN1; SMN2 3087/4885L3MBTL1 326/4885MC4R 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.