SCHEMBL4909286

SCHEMBL4909286

[O]C(=O)c1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.74
SRD5A2 P31213 2/20 0.68
L3MBTL1 Q9Y468 3/20 0.61
ATM Q13315 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
KMT2A Q03164 5/20 0.58
RAB9A P51151 5/20 0.58
MEN1 O00255 4/20 0.58
LMNA P02545 2/20 0.58
MAPT P10636 2/20 0.58
MAPK13 O15264 1/20 0.58
MAPK12 P53778 1/20 0.58
MAPK11 Q15759 1/20 0.58
MAPK14 Q16539 1/20 0.58
NPC1 O15118 4/20 0.56
HPGD P15428 3/20 0.56
CES2 O00748 1/20 0.55
CES1 P23141 1/20 0.55
ELANE P08246 1/20 0.54
TSHR P16473 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9066312 0.89 ALDH1A1 (0.93) ALDH1A1SRD5A2L3MBTL1ATMTDP1
SCHEMBL314267 0.89 ALDH1A1 (0.93) ALDH1A1SRD5A2L3MBTL1ATMTDP1
SCHEMBL22028 0.89
Benzophenone SCHEMBL665150 0.89 ALDH1A1 (0.93) ALDH1A1SRD5A2L3MBTL1ATMTDP1
Benzophenone SCHEMBL377243 0.89 ALDH1A1 (0.93) ALDH1A1SRD5A2L3MBTL1ATMTDP1
Benzophenone SCHEMBL4522894 0.89 ALDH1A1 (0.93) ALDH1A1SRD5A2L3MBTL1ATMTDP1
Hydrogen Sulfide SCHEMBL29219394 0.86 CES1 (0.58) ALDH1A1SRD5A2L3MBTL1ATMTDP1
Ammonia Solution, Strong SCHEMBL27572387 0.86 CES1 (0.58) ALDH1A1SRD5A2L3MBTL1ATMTDP1
Benzophenone SCHEMBL30537001 0.86 ALDH1A1 (1.00) ALDH1A1SRD5A2L3MBTL1ATMTDP1
Benzophenone SCHEMBL28491203 0.86 ALDH1A1 (1.00) ALDH1A1SRD5A2L3MBTL1ATMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080107829-A1 Cellulose compound, cellulose film, optical compensation sheet, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-05-08 US disclosed
US-4101464-A Process for preparing foamed solids using two or more azo compounds PENNWALT CORPORATION (US) 1978-07-18 US disclosed
US-4029615-A AZO COMPOUNDS PENNWALT CORPORATION (US) 1977-06-14 US disclosed
US-3993609-A ACID SENSITIVE AZO PROMOTERS PENNWALT CORPORATION (US) 1976-11-23 US disclosed