Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.52 |
| ▸ | ELANE | P08246 | 6/20 | 0.48 |
| ▸ | CD69 | Q07108 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13872664 | 0.86 | CYP2C19 (0.53) | CYP2C19SMN1; SMN2PTGDR2ELANECD69 | |
| SCHEMBL13757719 | 0.85 | CYP2C19 (0.74) | CYP2C19SMN1; SMN2PTGDR2ELANECD69 | |
| SCHEMBL17896571 | 0.84 | CYP2C19 (0.72) | CYP2C19SMN1; SMN2PTGDR2ELANECD69 | |
| SCHEMBL13872735 | 0.83 | CYP2C19 (0.50) | CYP2C19SMN1; SMN2PTGDR2ELANECD69 | |
| SCHEMBL5284414 | 0.83 | PTGDR2 (0.70) | CYP2C19SMN1; SMN2PTGDR2ELANECD69 | |
| SCHEMBL14076372 | 0.81 | CYP2C19 (0.68) | CYP2C19SMN1; SMN2PTGDR2ELANECD69 | |
| SCHEMBL13624055 | 0.81 | CYP2C19 (0.68) | CYP2C19SMN1; SMN2PTGDR2ELANECD69 | |
| SCHEMBL5321878 | 0.81 | CYP2C19 (0.68) | CYP2C19SMN1; SMN2PTGDR2ELANECD69 | |
| SCHEMBL4642505 | 0.81 | CYP2C19 (1.00) | CYP2C19SMN1; SMN2PTGDR2ELANECD69 | |
| SCHEMBL5320268 | 0.81 | CYP2C19 (0.68) | CYP2C19SMN1; SMN2PTGDR2ELANECD69 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312322-A1 | Organic Compounds | NOVARTIS AG (CH) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312322-A1 | Organic Compounds | NR3C2, MRGPRX2, HRH2 | CYP2C19 1491/4885SMN1; SMN2 2760/4885PTGDR2 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.