Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13757719 | 0.92 | CYP2C19 (0.74) | CYP2C19MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL7844241 | 0.86 | CYP2C19 (0.51) | CYP2C19MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL7846219 | 0.86 | SNCA (0.56) | CYP2C19MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL17896571 | 0.84 | CYP2C19 (0.72) | CYP2C19KMT2ASMN1; SMN2PTGDR2ELANE | |
| SCHEMBL5284414 | 0.83 | PTGDR2 (0.70) | CYP2C19MEN1KMT2ASMN1; SMN2PTGDR2 | |
| SCHEMBL13580642 | 0.83 | CYP2C19 (0.66) | CYP2C19POLBSMN1; SMN2PTGDR2NR1H4 | |
| SCHEMBL7844967 | 0.81 | CYP2C19 (0.52) | CYP2C19MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL5321878 | 0.81 | CYP2C19 (0.68) | CYP2C19SMN1; SMN2PTGDR2ELANECD69 | |
| SCHEMBL14076372 | 0.81 | CYP2C19 (0.68) | CYP2C19MEN1KMT2ASMN1; SMN2PTGDR2 | |
| SCHEMBL4909292 | 0.81 | CYP2C19 (0.68) | CYP2C19MEN1KMT2ASMN1; SMN2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291945-A1 | CYSTEINE PROTEASE INHIBITORS | TEIJIN PHARMA LIMITED (JP) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291945-A1 | CYSTEINE PROTEASE INHIBITORS | CTSE, SPINT2, CTSF | CYP2C19 1104/4885MEN1 1994/4885KMT2A 3986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.