Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5981873 | 1.00 | PTGS1 (0.30) | PTGS1AKR1C3 | |
| SCHEMBL4918084 | 0.82 | PTGS1 (0.30) | PTGS1AKR1C3 | |
| SCHEMBL4917633 | 0.82 | PTGS1 (0.30) | PTGS1AKR1C3 | |
| SCHEMBL897422 | 0.77 | AKR1C3 (0.34) | PTGS1AKR1C3 | |
| SCHEMBL4918003 | 0.75 | — | — | |
| SCHEMBL447741 | 0.72 | PTGS1 (0.36) | PTGS1AKR1C3 | |
| SCHEMBL447742 | 0.72 | PTGS1 (0.36) | PTGS1AKR1C3 | |
| SCHEMBL28004129 | 0.70 | APEX1 (0.32) | PTGS1AKR1C3 | |
| SCHEMBL10608647 | 0.70 | — | — | |
| SCHEMBL10608638 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112352170-A | Water extractable ophthalmic device | 鲍希与洛姆伯股份有限公司 | 2021-02-09 | — | — | CN | disclosed |
| US-20080038241-A1 | Self-Polishing Anti-Fouling coating Compositions Comprising An Enzyme | BIOLOCUS A/S (DK) | 2008-02-14 | — | — | US | disclosed |
| US-7112710-B2 | Preparation of silyl ketene acetal and disilyl ketene acetal | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2006-09-26 | — | — | US | disclosed |
| US-20050256329-A1 | Preparation of silyl ketene acetal and disilyl ketene acetal | KIYOMORI AYUMU | 2005-11-17 | — | — | US | disclosed |
| US-6960679-B2 | Preparation of silyl ketene acetal and disilyl ketene acetal | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20040215033-A1 | Preparation of silyl ketene acetal and disilyl ketene acetal | SHIN-ETSU CHEMICAL CO. LTD. (JP) | 2004-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256329-A1 | Preparation of silyl ketene acetal and disilyl ketene acetal | TREH, DEGS1, PHYKPL | PTGS1 1785/4885AKR1C3 138/4885 |
| US-20040215033-A1 | Preparation of silyl ketene acetal and disilyl ketene acetal | TREH, PHYKPL, KAT8 | PTGS1 2019/4885AKR1C3 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.