Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.47 |
| ▸ | ABAT | P80404 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938502 | 0.90 | ALDH1A1 (0.57) | ALDH1A1TSHRTDP1HPGDTRIM24 | |
| SCHEMBL524215 | 0.82 | KMT2A (0.55) | ALDH1A1TSHRTDP1HPGDTRIM24 | |
| SCHEMBL19628274 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1HPGDTRIM24 | |
| SCHEMBL564090 | 0.81 | ERN1 (0.54) | ALDH1A1TSHRTDP1HPGDTRIM24 | |
| SCHEMBL30842561 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TSHRTDP1HPGDTRIM24 | |
| SCHEMBL1312098 | 0.78 | ALDH1A1 (0.56) | ALDH1A1TSHRTDP1HPGDKMT2A | |
| SCHEMBL2391793 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TSHRTDP1HPGDTRIM24 | |
| SCHEMBL16471656 | 0.77 | ALDH1A1 (0.45) | ALDH1A1TSHRTDP1HPGDTRIM24 | |
| SCHEMBL335717 | 0.76 | ALDH1A1 (0.68) | ALDH1A1TSHRTDP1HPGDTRIM24 | |
| SCHEMBL29952908 | 0.76 | ALDH1A1 (0.68) | ALDH1A1TSHRTDP1HPGDTRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790896-B2 | RNA-selective probes for live cell imaging of nuclear structure and function | NEW YORK UNIVERSITY (US) | 2010-09-07 | — | — | US | disclosed |
| US-7790896-B2 | RNA-selective probes for live cell imaging of nuclear structure and function | NEW YORK UNIVERSITY (US) | 2010-09-07 | — | — | US | disclosed |
| EP-1984377-A2 | INHIBITORS OF TNF ALPHA , PDE4 AND B-RAF, COMPOSITIONS THEREOF AND METHODS OF USE THEREWITH | Signal Pharmaceuticals LLC (US) | 2008-10-29 | — | — | EP | disclosed |
| US-20080064037-A1 | RNA-SELECTIVE PROBES FOR LIVE CELL IMAGING OF NUCLEAR STRUCTURE AND FUNCTION | NEW YORK UNIVERSITY (US) | 2008-03-13 | — | — | US | disclosed |
| US-20080064037-A1 | RNA-SELECTIVE PROBES FOR LIVE CELL IMAGING OF NUCLEAR STRUCTURE AND FUNCTION | NEW YORK UNIVERSITY (US) | 2008-03-13 | — | — | US | disclosed |
| US-20080004271-A1 | Inhibitors of TNFalpha, PDE4 and B-RAF, compositions thereof and methods of use therewith | MCKENNA JEFFREY M | 2008-01-03 | — | — | US | disclosed |
| WO-2007084560-A2 | INHIBITORS OF TNFα, PDE4 AND B-RAF, COMPOSITIONS THEREOF AND METHODS OF USE THEREWITH | SIGNAL PHARMACEUTICALS, LLC (US) | 2007-07-26 | — | — | WO | disclosed |
| US-4003927-A | DIURETICS | MERCK & CO., INC. (US) | 1977-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064037-A1 | RNA-SELECTIVE PROBES FOR LIVE CELL IMAGING OF NUCLEAR STRUCTURE AND FUNCTION | SNRPE, HNRNPUL2, EFTUD2 | ALDH1A1 4222/4885TSHR 3429/4885TDP1 687/4885 |
| US-20080004271-A1 | Inhibitors of TNFalpha, PDE4 and B-RAF, compositions thereof and methods of use therewith | PDE4A, PDE4B, BRAF | ALDH1A1 1662/4885TSHR 1074/4885TDP1 411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.