Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11468589 | 0.85 | KDM4E (0.44) | KDM4EALDH1A1CYP1A2CYP2C19PLAU | |
| SCHEMBL28763047 | 0.85 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL3421628 | 0.85 | KDM4E (0.69) | KDM4EALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL30577888 | 0.85 | KDM4E (0.69) | KDM4EALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL8719138 | 0.84 | KDM4E (0.55) | KDM4EALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL4910445 | 0.84 | CA1 (0.59) | NPC1RAB9APKMSMN1; SMN2MAPT | |
| SCHEMBL15020009 | 0.83 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL15020198 | 0.83 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL11469358 | 0.82 | NPC1 (0.41) | KDM4EALDH1A1CYP1A2HPGDPLAU | |
| SCHEMBL21804751 | 0.81 | CES2 (0.62) | KDM4EALDH1A1NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352820-A | Expedient route to aryl propenoic esters | AMERICAN CYANAMID COMPANY | 1994-10-04 | — | — | US | claimed |
| US-5352820-A | Expedient route to aryl propenoic esters | AMERICAN CYANAMID COMPANY | 1994-10-04 | — | — | US | disclosed |