SCHEMBL4911071

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4920477	0.89	MAPT (0.68)	KMT2AMEN1MAPTTRPV1CASP3
	SCHEMBL4112088	0.88	KMT2A (0.75)	KMT2AMEN1MAPTTRPV1CASP3
	SCHEMBL481332	0.88	CA1 (0.61)	KMT2AMEN1MAPTNAMPTGAA
	Hydrochloric Acid SCHEMBL10669311	0.86	SMN1; SMN2 (0.59)	KMT2AMEN1MAPTNAMPTGAA
	SCHEMBL4104395	0.85	KMT2A (0.71)	KMT2AMEN1MAPTTRPV1CASP3
	SCHEMBL4922844	0.85	MAPT (0.75)	KMT2AMEN1MAPTTRPV1CASP3
	SCHEMBL1019967	0.85	SMN1; SMN2 (0.78)	KMT2AMEN1MAPTTRPV1CASP3
	SCHEMBL5187464	0.84	MAOA (0.70)	KMT2AMEN1MAPTTRPV1CASP3
	SCHEMBL4122842	0.84	KMT2A (0.69)	KMT2AMEN1MAPTTRPV1CASP3
	SCHEMBL4113307	0.83	MAPT (0.77)	KMT2AMEN1MAPTTRPV1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.