Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.36 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4914468 | 0.81 | PPARG (0.40) | HDAC1FSCN1HDAC6PPARGHDAC8 | |
| SCHEMBL1684175 | 0.79 | HDAC1 (0.38) | HDAC1FSCN1HDAC6HDAC4HDAC7 | |
| SCHEMBL4914229 | 0.79 | HDAC6 (0.48) | HDAC1FSCN1HDAC6HDAC4HDAC7 | |
| SCHEMBL4913900 | 0.72 | HDAC6 (0.48) | HDAC1HDAC6HDAC4HDAC7PPARG | |
| SCHEMBL4911360 | 0.69 | ROCK2 (0.37) | HDAC1HDAC6HDAC4HDAC7PPARG | |
| SCHEMBL2949469 | 0.66 | FSCN1 (0.42) | HDAC1FSCN1HDAC6HDAC4HDAC7 | |
| SCHEMBL4161051 | 0.66 | RAB9A (0.40) | HDAC1FSCN1HDAC6HDAC4HDAC7 | |
| SCHEMBL2950141 | 0.66 | PPARG (0.45) | HDAC1FSCN1HDAC6HDAC4HDAC7 | |
| SCHEMBL2943245 | 0.66 | FSCN1 (0.42) | HDAC1FSCN1HDAC6HDAC4HDAC7 | |
| SCHEMBL4932344 | 0.65 | HDAC6 (0.42) | HDAC1FSCN1HDAC6HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221154-A1 | HIV-INTEGRASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THEIR USE | PFIZER INC | 2008-09-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221154-A1 | HIV-INTEGRASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THEIR USE | TYMP, IMPDH1, POLB | HDAC1 18/4885FSCN1 4791/4885HDAC6 570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.