Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PTPRG | P23470 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4814523 | 0.94 | L3MBTL1 (0.58) | L3MBTL1KMT2AMEN1POLBDAO | |
| SCHEMBL4071760 | 0.71 | L3MBTL1 (0.63) | L3MBTL1KMT2AMEN1PTPRCPTPRG | |
| Hydrochloric Acid SCHEMBL10907120 | 0.64 | L3MBTL1 (0.56) | L3MBTL1KMT2AMEN1PTPRCPTPRG | |
| SCHEMBL5732708 | 0.64 | L3MBTL1 (0.82) | L3MBTL1KMT2AMEN1DAOTSHR | |
| Formic Acid SCHEMBL4814029 | 0.64 | POLB (0.36) | L3MBTL1POLBPTPRCTSHRGAA | |
| SCHEMBL9869963 | 0.62 | L3MBTL1 (0.59) | L3MBTL1KMT2ATSHRLMNA | |
| SCHEMBL14027069 | 0.59 | L3MBTL1 (0.42) | L3MBTL1KMT2AMEN1POLBTSHR | |
| SCHEMBL4823615 | 0.59 | NISCH (0.57) | L3MBTL1KMT2AMEN1TSHRGAA | |
| SCHEMBL4068865 | 0.59 | L3MBTL1 (0.46) | L3MBTL1KMT2AMEN1POLBTSHR | |
| SCHEMBL4068101 | 0.59 | NPC1 (0.47) | L3MBTL1KMT2AMEN1POLBDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269217-A1 | Melanocortin-4 receptor binding compounds and methods of use thereof | ORE PHARMACEUTICALS, INC. (US) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269217-A1 | Melanocortin-4 receptor binding compounds and methods of use thereof | MC4R, MC5R, MC3R | L3MBTL1 326/4885KMT2A 1838/4885MEN1 320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.