Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | ROS1 | P08922 | 1/20 | 0.41 |
| ▸ | MARK3 | P27448 | 1/20 | 0.41 |
| ▸ | LTK | P29376 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4826135 | 0.89 | METAP1 (0.53) | METAP1TDP2PGRSRD5A1SRD5A2 | |
| SCHEMBL29376113 | 0.89 | METAP1 (0.57) | METAP1TDP2PGRSRD5A1SRD5A2 | |
| SCHEMBL28126153 | 0.89 | METAP1 (0.57) | METAP1TDP2PGRSRD5A1SRD5A2 | |
| SCHEMBL40823 | 0.89 | METAP1 (0.57) | METAP1TDP2PGRSRD5A1SRD5A2 | |
| SCHEMBL28360994 | 0.86 | METAP1 (0.52) | METAP1TDP2PGRSRD5A1SRD5A2 | |
| SCHEMBL29569917 | 0.86 | METAP1 (0.52) | METAP1TDP2PGRSRD5A1SRD5A2 | |
| SCHEMBL3129344 | 0.86 | METAP1 (0.52) | METAP1TDP2PGRSRD5A1SRD5A2 | |
| Ammonia Solution, Strong SCHEMBL28144371 | 0.86 | METAP1 (0.55) | METAP1TDP2PGRSRD5A1SRD5A2 | |
| SCHEMBL27619851 | 0.86 | METAP1 (0.55) | METAP1TDP2PGRSRD5A1SRD5A2 | |
| SCHEMBL19417357 | 0.84 | METAP1 (0.43) | METAP1TDP2PGRSRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080075959-A1 | HIGH REFRACTIVE INDEX MONOMERS FOR OPTICAL APPLICATIONS | 3M INNOVATIVE PROPERTIES COMPANY | 2008-03-27 | — | — | US | disclosed |
| US-7297810-B2 | High refractive index monomers for optical applications | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-11-20 | — | — | US | disclosed |
| WO-2006073755-A1 | HIGH REFRACTIVE INDEX MONOMERS FOR OPTICAL APPLICATIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-07-13 | — | — | WO | disclosed |
| US-20060147703-A1 | High refractive index monomers for optical applications | 3M INNOVATIVE PROPERTIES COMPANY | 2006-07-06 | — | — | US | disclosed |