SCHEMBL28360994

SCHEMBL28360994

Brc1ccc2c(c1)-c1cc(Br)ccc1C2.Brc1ccc2c(c1)Cc1cc(Br)ccc1-2

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 1/20 0.52
CHEK2 O96017 1/20 0.52
ROS1 P08922 1/20 0.52
MARK3 P27448 1/20 0.52
LTK P29376 1/20 0.52
FLT4 P35916 1/20 0.52
KDR P35968 1/20 0.52
MINK1 Q8N4C8 1/20 0.52
AURKB Q96GD4 1/20 0.52
PBK Q96KB5 1/20 0.52
STK17A Q9UEE5 1/20 0.52
MAP4K5 Q9Y4K4 1/20 0.52
TDP2 O95551 1/20 0.50
PGR P06401 2/20 0.49
S100A4 P26447 1/20 0.44
SRD5A1 P18405 1/20 0.44
SRD5A2 P31213 1/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3129344 1.00 METAP1 (0.52) METAP1CHEK2ROS1MARK3LTK
SCHEMBL4826135 0.93 METAP1 (0.53) METAP1CHEK2ROS1MARK3LTK
SCHEMBL28126153 0.93 METAP1 (0.57) METAP1CHEK2ROS1MARK3LTK
SCHEMBL40823 0.93 METAP1 (0.57) METAP1CHEK2ROS1MARK3LTK
SCHEMBL3165396 0.93 CHEK2 (0.57) METAP1CHEK2ROS1MARK3LTK
SCHEMBL12117371 0.90 CHEK2 (0.55) METAP1CHEK2ROS1MARK3LTK
SCHEMBL27619851 0.90 METAP1 (0.55) METAP1CHEK2ROS1MARK3LTK
Ammonia Solution, Strong SCHEMBL28144371 0.90 METAP1 (0.55) METAP1CHEK2ROS1MARK3LTK
SCHEMBL23542831 0.86 L3MBTL1 (0.56) METAP1CHEK2ROS1MARK3LTK
SCHEMBL415882 0.86 ALDH1A1 (0.59) METAP1CHEK2ROS1MARK3LTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110801858-A Catalyst for preparing carbonyl compound by catalyzing benzyl compound oxidation, preparation method and application thereof 中国科学院山西煤炭化学研究所 2020-02-18 CN claimed
CN-110801858-B Catalyst for preparing carbonyl compound by catalyzing benzyl compound oxidation, preparation method and application thereof 中国科学院山西煤炭化学研究所 2021-12-07 CN disclosed
CN-110801858-A Catalyst for preparing carbonyl compound by catalyzing benzyl compound oxidation, preparation method and application thereof 中国科学院山西煤炭化学研究所 2020-02-18 CN disclosed