SCHEMBL491257

SCHEMBL491257

CCCCCC(CC)(CC)Oc1ccccc1O.Cc1ccccc1-c1ccnnn1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 7/20 0.36
CNR2 P34972 7/20 0.36
TLR8 Q9NR97 1/20 0.32
LTB4R Q15722 2/20 0.32
LTB4R2 Q9NPC1 2/20 0.32
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
NFKB1 P19838 1/20 0.31
CYP2C19 P33261 1/20 0.31
RAB9A P51151 1/20 0.31
NFKB2 Q00653 1/20 0.31
KMT2A Q03164 1/20 0.31
RELA Q04206 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1276209 0.90 CNR1 (0.36) CNR1CNR2TLR8MEN1CYP1A2
SCHEMBL64303 0.90 CNR1 (0.45) CNR1CNR2TLR8MEN1MAPT
SCHEMBL28914891 0.89 CNR1 (0.44) CNR1CNR2TLR8MEN1MAPT
Guaiacol SCHEMBL29291132 0.89 CNR1 (0.44) CNR1CNR2TLR8MEN1MAPT
SCHEMBL1372006 0.86 CNR1 (0.35) CNR1CNR2TLR8CYP1A2CYP2C9
SCHEMBL16167433 0.82 CNR1 (0.39) CNR1CNR2MEN1MAPTKMT2A
SCHEMBL28576458 0.82 CNR1 (0.33) CNR1CNR2TLR8CYP1A2CYP2C9
SCHEMBL15901669 0.80 CNR1 (0.35) CNR1CNR2
SCHEMBL28235565 0.79 PPARA (0.39) CNR1CNR2MEN1MAPTKMT2A
SCHEMBL1722938 0.79 LMNA (0.34) CNR1CNR2TLR8CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112544571-B Establishment and application of caenorhabditis elegans model for evaluating safety and efficacy of sun-screening agent 上海应用技术大学 2023-03-03 CN disclosed
CN-112544571-A Establishment and application of caenorhabditis elegans model for evaluating safety and efficacy of sun-screening agent 上海应用技术大学 2021-03-26 CN disclosed
US-8105616-B2 Skin-pampering cream lotion BEIERSDORF AG (DE) 2012-01-31 US disclosed
US-20060193806-A1 Skin-pampering cream lotion BEIERSDORF AG 2006-08-31 US disclosed