SCHEMBL1372006

SCHEMBL1372006

CCCCCC(CC)(CC)Oc1ccccc1-c1ccnnn1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 3/20 0.35
CNR2 P34972 3/20 0.35
TLR8 Q9NR97 2/20 0.33
CYP1A2 P05177 1/20 0.32
CYP19A1 P11511 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
PDE5A O76074 2/20 0.31
PDE4A P27815 2/20 0.31
PDE4B Q07343 2/20 0.31
PDE4C Q08493 2/20 0.31
PDE4D Q08499 2/20 0.31
TLR4 O00206 1/20 0.30
TLR3 O15455 1/20 0.30
TLR5 O60602 1/20 0.30
TLR2 O60603 1/20 0.30
CAMK2B Q13554 1/20 0.30
CAMK2G Q13555 1/20 0.30
CAMK2D Q13557 1/20 0.30
CAMK1 Q14012 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28576458 0.93 CNR1 (0.33) CNR1CNR2TLR8CYP1A2CYP19A1
SCHEMBL1722938 0.89 LMNA (0.34) CNR1CNR2TLR8CYP1A2CYP19A1
SCHEMBL1276209 0.88 CNR1 (0.36) CNR1CNR2TLR8CYP1A2CYP19A1
SCHEMBL64303 0.88 CNR1 (0.45) CNR1CNR2TLR8
SCHEMBL29189936 0.88 CNR1 (0.40) CNR1CNR2TLR8CYP1A2CYP2C9
Guaiacol SCHEMBL29291132 0.88 CNR1 (0.44) CNR1CNR2TLR8
SCHEMBL28914891 0.88 CNR1 (0.44) CNR1CNR2TLR8
SCHEMBL3793515 0.86 PDE5A (0.35) CNR1CNR2TLR8CYP1A2CYP19A1
SCHEMBL491257 0.86 CNR1 (0.36) CNR1CNR2TLR8CYP1A2CYP2C9
SCHEMBL28590842 0.84 CYP1A2 (0.39) CNR1CNR2TLR8CYP1A2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2575750-A2 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE International Flora Technologies, Ltd. (US) 2013-04-10 EP claimed
WO-2011149929-A2 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE INTERNATIONAL FLORA TECHNOLOGIES LTD. (US) 2011-12-01 WO claimed
US-20110286946-A1 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE INTERNATIONAL FLORA TECHNOLOGIES LTD. (US) 2011-11-24 US claimed
CN-119564561-A Mousse type sun-proof cosmetic composition and preparation method thereof 广东博然堂生物科技有限公司 2025-03-07 CN disclosed
CN-114983866-B Reticular macromolecule sun-proof film cosmetic composition 广州科创材料科技有限公司 2024-09-13 CN disclosed
CN-117083072-A Cosmetic composition 奇华顿股份有限公司 2023-11-17 CN disclosed
CN-113616540-B Novel occlusive formulations 株式会社LG生活健康 2023-11-03 CN disclosed
US-20230248634-A1 UV-BLOCKING COSMETIC COMPOSITION HAVING INCREASED UV-BLOCKING EFFICIENCY DUE TO HEAT AND UV LIGHT LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2023-08-10 US disclosed
CN-116490598-A Detergent compositions with enhanced efficacy delivery of substances 株式会社LG生活健康 2023-07-25 CN disclosed
CN-110049754-B Fatty acid ethyl ester for cosmetics CJ第一制糖株式会社 2022-12-06 CN disclosed
CN-113226362-A Topical formulations for delivery of microbially-derived materials 马特里西斯生物科学公司 2021-08-06 CN disclosed
US-20150157996-A1 EMULSION COMPOSITIONS AND APPLICATIONS THEREFOR MOMENTIVE PERFORMANCE MATERIALS INC. 2015-06-11 US disclosed
US-8496974-B2 Method for preparing a composition comprising a compound mixture and a carrier agent OY GRANULA AB LTD (FI) 2013-07-30 US disclosed
US-20120289649-A1 Hydrophilic/Lipophilic Modified Polysiloxanes As Emsulsifiers Momentive-Performance Materials GmbH (DE) 2012-11-15 US disclosed
EP-2504381-A1 HYDROPHILIC/LIPOPHILIC MODIFIED POLYSILOXANES AS EMULSIFIERS Momentive Performance Materials GmbH (DE) 2012-10-03 EP disclosed
US-20110286946-A1 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE INTERNATIONAL FLORA TECHNOLOGIES LTD. (US) 2011-11-24 US disclosed
WO-2011064255-A1 HYDROPHILIC/LIPOPHILIC MODIFIED POLYSILOXANES AS EMULSIFIERS MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2011-06-03 WO disclosed
EP-2252154-A2 METHOD FOR MINIMIZING THE CYTOTOXICITY OF THE EFFECTIVE AGENT IN A COMPOSITION THAT IS ADMINISTERED TO A MAMMAL OR GETS INTO CONTACT WITH A MAMMAL Oy Granula AB LTD (FI) 2010-11-24 EP disclosed
US-20100129304-A1 METHOD FOR PREPARING A COMPOSITION COMPRISING A COMPOUND MIXTURE AND A CARRIER AGENT OY GRANULA AB LTD (FI) 2010-05-27 US disclosed
WO-2009101261-A2 METHOD FOR MINIMIZING THE CYTOTOXICITY OF THE EFFECTIVE AGENT IN A COMPOSITION THAT IS ADMINISTERED TO A MAMMAL OR GETS INTO CONTACT WITH A MAMMAL OY GRANULA AB LTD (FI) 2009-08-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120289649-A1 Hydrophilic/Lipophilic Modified Polysiloxanes As Emsulsifiers MGLL, ELOVL1, PLOD3 CNR1 2843/4885CNR2 3048/4885TLR8 999/4885
US-20150157996-A1 EMULSION COMPOSITIONS AND APPLICATIONS THEREFOR POLR1C, POLQ, POLH CNR1 4497/4885CNR2 4792/4885TLR8 951/4885
US-20100129304-A1 METHOD FOR PREPARING A COMPOSITION COMPRISING A COMPOUND MIXTURE AND A CARRIER AGENT H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, BAK1, PMAIP1 CNR1 3025/4885CNR2 2978/4885TLR8 1707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.