SCHEMBL491287

SCHEMBL491287

Fc1cccc(Br)c1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29596433 1.00
Fluorobenzene SCHEMBL28860300 0.88 HTT (0.36)
SCHEMBL610147 0.84
SCHEMBL6009043 0.81 CES2 (0.39)
SCHEMBL355898 0.77
SCHEMBL361070 0.77
SCHEMBL29384418 0.77
SCHEMBL22129740 0.76 CA1 (0.37)
SCHEMBL29572769 0.75
SCHEMBL153356 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119143706-A Efficient and environment-friendly 1-bromo-dibenzofuran synthesis process 棓诺(苏州)新材料有限公司 2024-12-17 CN claimed
CN-107978795-B Novel lithium ion battery electrolyte 香河昆仑化学制品有限公司 2020-07-31 CN claimed
CN-108276447-B Thermally-excited delayed fluorescence guest material and preparation and application thereof 黑龙江大学 2020-03-31 CN claimed
CN-108276445-B Thermal excitation delayed fluorescence main body material and preparation and application thereof 黑龙江大学 2020-03-31 CN claimed
CN-108276445-A A kind of thermal excitation delayed fluorescence material of main part and its preparation and application 黑龙江大学 2018-07-13 CN claimed
EP-2016039-B1 TERPHENYL DERIVATIVES FOR TREATMENT OF ALZHEIMER' S DISEASE ORTHO MCNEIL JANSSEN PHARM (US) 2012-08-01 EP claimed
US-8106236-B2 Triaryl compounds and derivates thereof ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2012-01-31 US claimed
US-7956222-B2 Methods for producing dibromofluorobenzene derivatives EISAI R&D MANAGEMENT CO., LTD (JP) 2011-06-07 US claimed
EP-1847524-B1 Terphenyl derivatives for treatment of Alzheimer's disease CELLZOME LTD (GB) 2009-10-14 EP claimed
EP-1849762-B1 Substituted biphenyl carboxylic acids and derivatives thereof CELLZOME LTD (GB) 2009-07-15 EP claimed
US-20070293567-A1 SUBSTITUTED BIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES THEREOF ORTHO-MCNEIL PHARMACEUTICAL, INC. 2007-12-20 US claimed
WO-2007124351-A1 TERPHENYL DERIVATIVES FOR TREATMENT OF ALZHEIMER' S DISEASE ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2007-11-01 WO claimed
US-20070254957-A1 TRIARYL COMPOUNDS AND DERIVATES THEREOF ORTHO-MCNEIL PHARMACEUTICAL, INC. 2007-11-01 US claimed
WO-2007124394-A1 SUBSTITUTED BIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES THEREOF ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2007-11-01 WO claimed
EP-1849762-A1 Substituted biphenyl carboxylic acids and derivatives thereof Cellzome (UK) Ltd. (GB) 2007-10-31 EP claimed
EP-1847524-A1 Terphenyl derivatives for treatment of Alzheimer's disease Cellzome (UK) Ltd. (GB) 2007-10-24 EP claimed
EP-1780192-A1 METHOD FOR PRODUCING DIBROMOFLUOROBENZENE DERIVATIVE Eisai R&D Management Co., Ltd. (JP) 2007-05-02 EP claimed
EP-0761627-B1 Process for the preparation of p-bromofluorobenzene BROMINE COMPOUNDS LTD (IL) 2000-04-05 EP claimed
EP-0466698-A1 PREPARATION OF 2-HALOFLUOROBENZENE MALLINCKRODT, INC. (US) 1992-01-22 EP claimed
WO-1990011987-A1 PREPARATION OF 2-HALOFLUOROBENZENE MALLINCKRODT, INC. (US) 1990-10-18 WO claimed