Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PKLR | P30613 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL610147 | 0.97 | — | — | |
| Methyl Alcohol SCHEMBL27969294 | 0.88 | CES2 (0.42) | CES2CES1ACHENFE2L2BCHE | |
| SCHEMBL491287 | 0.81 | — | — | |
| SCHEMBL29596433 | 0.81 | — | — | |
| Formic Acid SCHEMBL27905472 | 0.81 | ERN1 (0.45) | CES2CES1NFE2L2BCHEALB | |
| Benzene SCHEMBL28220490 | 0.79 | HTT (0.36) | CES2CES1ACHENFE2L2BCHE | |
| SCHEMBL3563564 | 0.77 | — | — | |
| SCHEMBL2263095 | 0.77 | — | — | |
| SCHEMBL3158194 | 0.77 | — | — | |
| SCHEMBL1494523 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7012079-B1 | Optically pure camptothecin analogues | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2006-03-14 | — | — | US | disclosed |
| CN-1195757-C | Optically pure camptothecin analogues | SOD CONSEILS RECH APPLIC (FR) | 2005-04-06 | — | — | CN | disclosed |
| EP-0995753-B1 | Method for manufacturing fluoroaryl magnesium halide | NIPPON CATALYTIC CHEM IND (JP) | 2004-02-18 | — | — | EP | disclosed |
| CN-1345321-A | Optically pure camptothecin analogs | SOD CONSEILS RECH APPLIC (FR) | 2002-04-17 | — | — | CN | disclosed |
| US-6235222-B1 | REACTING, IN SOLVENT CONTAINING CHAIN ETHER SOLVENT, HYDROCARBON MAGNESIUM HALIDE WITH FLUOROARYL HALIDE | NIPPON SHOKUBAI CO., LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0995753-A2 | Method for manufacturing fluoroaryl magnesium halide | Nippon Shokubai Co., Ltd. (JP) | 2000-04-26 | — | — | EP | disclosed |