Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 9/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.66 |
| ▸ | CCR4 | P51679 | 3/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CDK7 | P50613 | 1/20 | 0.45 |
| ▸ | CCNH | P51946 | 1/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.45 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.45 |
| ▸ | S100A9 | P06702 | 3/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4904763 | 0.84 | CCR2 (0.67) | CCR2CYP2C9CYP3A4CYP2C19CCR4 | |
| SCHEMBL4902561 | 0.84 | CCR2 (0.72) | CCR2CYP2C9CYP3A4CYP2C19CCR4 | |
| SCHEMBL4903010 | 0.84 | CCR2 (0.76) | CCR2CYP2C9CYP3A4CYP2C19CCR4 | |
| SCHEMBL4907549 | 0.84 | CCR2 (0.69) | CCR2CYP2C9CYP3A4CYP2C19CCR4 | |
| SCHEMBL4907410 | 0.83 | CCR2 (0.74) | CCR2CYP2C9CYP3A4CYP2C19CCR4 | |
| SCHEMBL4907585 | 0.83 | CCR2 (0.71) | CCR2CYP2C9CYP3A4CYP2C19CCR4 | |
| SCHEMBL14513369 | 0.82 | CCR2 (0.67) | CCR2CYP2C9CYP3A4CYP2C19CCR4 | |
| SCHEMBL4912251 | 0.82 | CCR2 (0.67) | CCR2CYP2C9CYP3A4CYP2C19CCR4 | |
| SCHEMBL4912569 | 0.82 | CCR2 (0.70) | CCR2CYP2C9CYP3A4CYP2C19CCR4 | |
| SCHEMBL4912263 | 0.82 | CCR2 (0.67) | CCR2CYP2C9CYP3A4CYP2C19CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293720-A1 | Pyridinyl Sulfonamide Modulators of Chemokine Receptors | GLAXO GROUP LIMITED (GB) | 2008-11-27 | — | — | US | disclosed |
| US-20080293720-A1 | Pyridinyl Sulfonamide Modulators of Chemokine Receptors | GLAXO GROUP LIMITED (GB) | 2008-11-27 | — | — | US | disclosed |
| US-20080293720-A1 | Pyridinyl Sulfonamide Modulators of Chemokine Receptors | GLAXO GROUP LIMITED (GB) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293720-A1 | Pyridinyl Sulfonamide Modulators of Chemokine Receptors | CCR2, CCR1, CCRL2 | CCR2 1/4885CYP2C9 1296/4885CYP3A4 1414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.