Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.57 |
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 5/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PLEC | Q15149 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4912916 | 1.00 | KMT2A (0.57) | KMT2AMAPTMEN1POLBGAA | |
| SCHEMBL12416949 | 0.85 | CA2 (0.62) | ALDH1A1 | |
| SCHEMBL3917470 | 0.81 | KMT2A (0.67) | KMT2AMAPTMEN1POLBGAA | |
| SCHEMBL3917467 | 0.81 | KMT2A (0.67) | KMT2AMAPTMEN1POLBGAA | |
| SCHEMBL4922100 | 0.80 | KMT2A (0.51) | KMT2AMAPTMEN1POLBGAA | |
| SCHEMBL28985920 | 0.79 | KMT2A (0.51) | KMT2AMAPTMEN1POLBGAA | |
| SCHEMBL10623179 | 0.78 | AMY1A (0.56) | KMT2AMAPTMEN1POLBGAA | |
| SCHEMBL16476564 | 0.78 | AMY1A (0.56) | KMT2AMAPTMEN1POLBGAA | |
| SCHEMBL18873292 | 0.78 | AMY1A (0.56) | KMT2AMAPTMEN1POLBGAA | |
| SCHEMBL28985919 | 0.78 | KMT2A (0.57) | KMT2AMAPTMEN1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080146772-A1 | MATERIALS AND METHODS FOR CO-CRYSTAL CONTROLLED SOLID-STATE SYNTHESIS OF IMIDES AND IMINES | UNIVERSITY OF SOUTH FLORIDA (US) | 2008-06-19 | — | — | US | disclosed |