Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 20/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14147356 | 0.84 | PTGES (0.56) | PTGESJAK2 | |
| SCHEMBL4785925 | 0.82 | PTGES (0.49) | PTGESJAK2CYP2C9 | |
| SCHEMBL4879655 | 0.79 | PTGES (0.53) | PTGESJAK2CYP2C9 | |
| SCHEMBL4924204 | 0.78 | PTGES (0.49) | PTGESCYP2C9 | |
| SCHEMBL2361007 | 0.75 | PTGES (0.61) | PTGESJAK2CYP2C9 | |
| SCHEMBL4786267 | 0.75 | PTGES (0.58) | PTGESJAK2 | |
| SCHEMBL4785278 | 0.74 | PTGES (0.52) | PTGES | |
| SCHEMBL4786533 | 0.73 | PTGES (0.45) | PTGES | |
| SCHEMBL3801179 | 0.70 | PTGES (0.66) | PTGESJAK2 | |
| SCHEMBL14146871 | 0.69 | PTGES (0.47) | PTGESCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008084218-A1 | BENZAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008084218-A1 | BENZAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-17 | — | — | WO | disclosed |