Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 16/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785925 | 0.90 | PTGES (0.49) | PTGESMAPK14CSNK1DCSNK1EPTGS1 | |
| SCHEMBL4924204 | 0.90 | PTGES (0.49) | PTGESMAPK14CSNK1DCSNK1EPTGS1 | |
| SCHEMBL14147356 | 0.88 | PTGES (0.56) | PTGESMAPK14KDM4ENPC1RAB9A | |
| SCHEMBL4913832 | 0.79 | PTGES (0.51) | PTGESCYP2C9JAK2 | |
| SCHEMBL2360992 | 0.78 | PTGES (0.59) | PTGESJAK2 | |
| SCHEMBL2361558 | 0.78 | PTGES (0.53) | PTGESKDM4ECYP2C9JAK2 | |
| SCHEMBL14147374 | 0.78 | PTGES (0.47) | PTGESMAPK14CSNK1DCSNK1EPTGS1 | |
| SCHEMBL2361014 | 0.76 | PTGES (0.43) | PTGESMAPK14CYP2C9JAK2 | |
| SCHEMBL2360673 | 0.75 | DGAT1 (0.56) | PTGESMAPK14KDM4ENPC1RAB9A | |
| SCHEMBL4786267 | 0.75 | PTGES (0.58) | PTGESMAPK14KDM4EJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008084218-A1 | BENZAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008084218-A1 | BENZAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-17 | — | — | WO | disclosed |