Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 15/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4913567 | 0.81 | DGAT1 (0.52) | DGAT1 | |
| SCHEMBL4886823 | 0.79 | DGAT1 (0.56) | DGAT1 | |
| SCHEMBL4921471 | 0.71 | DGAT1 (0.73) | DGAT1 | |
| SCHEMBL6031922 | 0.70 | DGAT1 (0.62) | DGAT1RAB9A | |
| SCHEMBL594904 | 0.70 | DGAT1 (0.62) | DGAT1RAB9A | |
| SCHEMBL3634560 | 0.70 | DGAT1 (0.62) | DGAT1RAB9A | |
| SCHEMBL594903 | 0.70 | DGAT1 (0.62) | DGAT1RAB9A | |
| SCHEMBL594902 | 0.70 | DGAT1 (0.62) | DGAT1RAB9A | |
| SCHEMBL14124762 | 0.70 | DGAT1 (0.69) | DGAT1SMN1; SMN2RAB9A | |
| SCHEMBL6067937 | 0.69 | CYP2A6 (0.67) | CYP2A6RAB9AAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064717-A1 | Inhibitors of diacylglycerol O-acyltransferase type 1 enzyme | ABBOTT LABORATORIES | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064717-A1 | Inhibitors of diacylglycerol O-acyltransferase type 1 enzyme | DGAT1, DGAT2, DLAT | DGAT1 1/4885CYP2A6 1120/4885SMN1; SMN2 4202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.