SCHEMBL491407

SCHEMBL491407

C=C(C)C(=O)NCCC#N

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.38
HSD17B10 Q99714 1/20 0.36
MCL1 Q07820 3/20 0.35
TGFBR1 P36897 1/20 0.33
MAPK1 P28482 1/20 0.31
CYP1A2 P05177 1/20 0.30
TP53 P04637 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28907469 0.89 MCL1 (0.32) MAPTMCL1TGFBR1
SCHEMBL1681786 0.88 KDM4E (0.35) MCL1TGFBR1MAPK1ALDH1A1
SCHEMBL28535684 0.86 PAOX (0.41) MCL1MAPK1
SCHEMBL21624427 0.84 PAOX (0.40) MAPK1
SCHEMBL245262 0.80
SCHEMBL316224 0.79 TGFBR1 (0.41) HSD17B10TGFBR1MAPK1CYP1A2ALDH1A1
SCHEMBL21315459 0.79 MCL1 (0.58) MAPTHSD17B10MCL1TGFBR1CYP1A2
SCHEMBL48475 0.78
SCHEMBL16931675 0.78 MAPT (0.37) MAPTHSD17B10MCL1ALDH1A1
SCHEMBL21623913 0.76 MCL1 (0.55) MAPTHSD17B10MCL1MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 309 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260040695-A1 A METHOD TO GENERATE CONDUCTIVE POLYMER NEWSOUTH INNOVATIONS PTY LTD (AU) 2026-02-05 US claimed
EP-4562077-A1 A METHOD TO GENERATE CONDUCTIVE POLYMER NewSouth Innovations Pty Limited (AU) 2025-06-04 EP claimed
WO-2024020649-A1 A METHOD TO GENERATE CONDUCTIVE POLYMER NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2024-02-01 WO claimed
WO-2022261721-A1 HEALABLE AND REPROCESSABLE COMPOSITIONS DEAKIN UNIVERSITY (AU) 2022-12-22 WO claimed
US-10551345-B2 Poly and copoly(N-vinylamide)s and their use in capillary electrophoresis APPLIED BIOSYSTEMS, LLC (US) 2020-02-04 US claimed
US-20170356877-A1 POLY AND COPOLY(N-VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS APPLIED BIOSYSTEMS, LLC (US) 2017-12-14 US claimed
US-9671367-B2 Poly and copoly(N-vinylamide)s and their use in capillary electrophoresis APPLIED BIOSYSTEMS, LLC (US) 2017-06-06 US claimed
US-20150159009-A1 GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS APPLIED BIOSYSTEMS LLC (US) 2015-06-11 US claimed
US-20140209461-A1 Poly and Copoly(N-vinylamide)s and Their Use In Capillary Electrophoresis APPLIED BIOSYSTEMS, LLC (US) 2014-07-31 US claimed
US-8603709-B2 Polyurethane anticurl backside coating (ACBC) photoconductors XEROX CORPORATION (US) 2013-12-10 US claimed
EP-1967907-A1 Hole Blocking Layer Containing Photoconductors Xerox Corporation (US) 2008-09-10 EP claimed
US-20070248813-A1 Imaging member having styrene XEROX CORPORATION (US) 2007-10-25 US claimed
CN-1816573-A (N-vinylamide) polymers and copolymers and their use in capillary electrophoresis APPLERA CORP (US) 2006-08-09 CN claimed
EP-1636279-A1 POLY AND COPOLY (N -VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS Applera Corporation (US) 2006-03-22 EP claimed
US-20050234166-A1 Graft copolymers, their preparation and use in capillary electrophoresis APPLIED BIOSYSTEMS, INC. 2005-10-20 US claimed
EP-1539846-A1 GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS Applera Corporation (US) 2005-06-15 EP claimed
US-20050025741-A1 Copolymers with (meth)acrylamides; improved separation of polynucleotides APPLIED BIOSYSTEMS, LLC 2005-02-03 US claimed
WO-2004104054-A1 POLY AND COPOLY (N-VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS APPLERA CORPORATION (US) 2004-12-02 WO claimed
WO-2004011513-A1 GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS APPLERA CORPORATION (US) 2004-02-05 WO claimed
EP-0262796-B1 Resin compositons and their manufacturing method TORAY INDUSTRIES (JP) 1993-11-03 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260040695-A1 A METHOD TO GENERATE CONDUCTIVE POLYMER PIEZO1, LCP1, MTCL3 MAPT 9/4885HSD17B10 4872/4885MCL1 2852/4885
US-20050025741-A1 Copolymers with (meth)acrylamides; improved separation of polynucleotides POLI, PCNA, POLL MAPT 1487/4885HSD17B10 4181/4885MCL1 439/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.