SCHEMBL491433

SCHEMBL491433

N#Cc1cccc(O)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
LMNA P02545 3/20 0.52
HPGD P15428 3/20 0.52
ALOX15 P16050 3/20 0.52
HSD17B10 Q99714 3/20 0.52
CA2 P00918 3/20 0.52
CA1 P00915 2/20 0.52
EGFR P00533 2/20 0.52
FYN P06241 2/20 0.52
MMP9 P14780 2/20 0.52
RECQL P46063 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
ADAMTS4 O75173 1/20 0.52
MMP2 P08253 1/20 0.52
MMP8 P22894 1/20 0.52
CA6 P23280 1/20 0.52
CDK2 P24941 1/20 0.52
MMP12 P39900 1/20 0.52
ADAMTS5 Q9UNA0 1/20 0.52
CXCR2 P25025 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31609682 1.00 ALDH1A1 (0.52) ALDH1A1LMNAHPGDALOX15HSD17B10
Lithium SCHEMBL31158051 0.98 ALDH1A1 (0.50) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL4076853 0.98 ALDH1A1 (0.50) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL3032522 0.87 CXCR2 (0.47) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL15548582 0.81 ESR2 (0.44) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL21173600 0.80 ESR2 (0.52) ALDH1A1CA2CA1CXCR2ESR2
SCHEMBL29392995 0.79
SCHEMBL5756 0.79
Catechol SCHEMBL28751649 0.79 KDM4E (0.56) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL27875336 0.79 TSHR (0.50) ALDH1A1LMNAHPGDALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260002924-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-01-01 US claimed
CN-119570018-A Arc-resistant polyaryletherketone matrix and preparation method thereof, and arc-resistant composite material and preparation method thereof 江苏君华特种高分子材料股份有限公司 2025-03-07 CN claimed
EP-4477693-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS Korea Research Institute of Chemical Technology (KR) 2024-12-18 EP claimed
CN-220911032-U Pharmaceutical intermediate prepares cooling device 江西荣盛生物医药有限公司 2024-05-07 CN claimed
CN-117209757-A Preparation method of high-cyano-density soluble heat-resistant phthalonitrile resin containing branched cyano groups 华东理工大学 2023-12-12 CN claimed
CN-112974193-B Multilayer protective film with wear resistance 山西顶新薄膜科技股份有限公司 2023-11-14 CN claimed
WO-2023195794-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS 한국화학연구원 2023-10-12 WO claimed
CN-115404039-B Polyurethane adhesive and preparation method and application thereof 杭州之江有机硅化工有限公司 2023-06-16 CN claimed
CN-115404039-A Polyurethane adhesive and preparation method and application thereof 杭州之江有机硅化工有限公司 2022-11-29 CN claimed
EP-3247698-B1 CRYSTALLINE MODIFICATION OF PROPANIL UPL LTD (IN) 2022-10-19 EP claimed
WO-2007124351-A1 TERPHENYL DERIVATIVES FOR TREATMENT OF ALZHEIMER' S DISEASE ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2007-11-01 WO claimed
US-20070254957-A1 TRIARYL COMPOUNDS AND DERIVATES THEREOF ORTHO-MCNEIL PHARMACEUTICAL, INC. 2007-11-01 US claimed
EP-1847524-A1 Terphenyl derivatives for treatment of Alzheimer's disease Cellzome (UK) Ltd. (GB) 2007-10-24 EP claimed
CN-1254466-C Process for preparing 3,4-dihydroxy benzonitrile UBE INDUSTRIES (JP) 2006-05-03 CN claimed
EP-1540680-A1 N-TYPE METAL OXIDE SEMICONDUCTOR SPECTRALLY SENSITIZED WITH A CATIONIC SPECTRAL SENSITIZER Agfa-Gevaert (BE) 2005-06-15 EP claimed
US-20040094198-A1 n-type Metal oxide semiconductor spectrally sensitized with a cationic spectral sensitizer AGFA-GEVAERT (BE) 2004-05-20 US claimed
WO-2004025674-A1 N-TYPE METAL OXIDE SEMICONDUCTOR SPECTRALLY SENSITIZED WITH A CATIONIC SPECTRAL SENSITIZER AGFA-GEVAERT (BE) 2004-03-25 WO claimed
CN-1392138-A Process for preparing 3,4-dihydroxy benzonitrile UBE INDUSTRIES (JP) 2003-01-22 CN claimed
EP-0936860-B1 COMPOSITION AND METHOD FOR TREATING PLANTS WITH EXOGENOUS CHEMICALS MONSANTO TECHNOLOGY LLC (US) 2002-02-20 EP claimed
EP-0074116-B1 PROCESS FOR PRODUCING HYDROXYBENZONITRILES Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1986-01-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260002924-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS FGB, NR4A1, CYP2E1 ALDH1A1 105/4885LMNA 719/4885HPGD 2585/4885
US-20070254957-A1 TRIARYL COMPOUNDS AND DERIVATES THEREOF BACE1, BACE2, APP ALDH1A1 1583/4885LMNA 1012/4885HPGD 2714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.