SCHEMBL4914604

SCHEMBL4914604

CC(C)Oc1ccc(-n2c(C(=O)O)c(N(C)C(=O)C(C)(C)C)c3cc(Oc4ccc(C(F)(F)F)cc4)ccc32)cc1

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 17/20 0.48
PPARA Q07869 7/20 0.48
PTGES O14684 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4922054 0.92 PPARG (0.47) PPARGPPARAPTGES
SCHEMBL4924503 0.86 PTGES (0.39) PPARGPPARAPTGES
SCHEMBL4926810 0.85 PPARG (0.42) PPARGPPARAPTGES
SCHEMBL1407250 0.84 PPARG (0.51) PPARGPPARAPTGES
SCHEMBL4228390 0.83 PPARG (0.50) PPARGPPARAPTGES
SCHEMBL5319899 0.83 PPARG (0.50) PPARGPPARAPTGES
SCHEMBL4924007 0.83 PPARG (0.47) PPARGPPARAPTGES
SCHEMBL4923531 0.82 PPARG (0.48) PPARGPPARAPTGES
SCHEMBL333811 0.81 PPARG (0.50) PPARGPPARAPTGES
SCHEMBL4914621 0.80 PPARG (0.47) PPARGPPARAPTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080249091-A1 Indoles Useful in the Treatment of Inflammation BIOLIPOX AB (SE) 2008-10-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080249091-A1 Indoles Useful in the Treatment of Inflammation IDO1, IDO2, ARG1 PPARG 2586/4885PPARA 3339/4885PTGES 35/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.