Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGPL1 | O95470 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 2/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 16/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4914704 | 1.00 | SGPL1 (0.46) | SGPL1ACACBACACAP2RY12 | |
| SCHEMBL12903164 | 0.92 | P2RY12 (0.44) | P2RY12 | |
| SCHEMBL4917981 | 0.90 | SGPL1 (0.46) | SGPL1ACACBACACAP2RY12 | |
| SCHEMBL4915924 | 0.90 | SGPL1 (0.46) | SGPL1ACACBACACAP2RY12 | |
| SCHEMBL908338 | 0.88 | SGPL1 (0.49) | SGPL1ACACBACACAP2RY12 | |
| SCHEMBL908339 | 0.88 | SGPL1 (0.49) | SGPL1ACACBACACAP2RY12 | |
| SCHEMBL908080 | 0.87 | SGPL1 (0.43) | SGPL1ACACBACACAP2RY12 | |
| SCHEMBL908082 | 0.87 | SGPL1 (0.43) | SGPL1ACACBACACAP2RY12 | |
| SCHEMBL907939 | 0.86 | SGPL1 (0.44) | SGPL1ACACBACACAP2RY12 | |
| SCHEMBL907938 | 0.86 | SGPL1 (0.44) | SGPL1ACACBACACAP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080045525-A1 | Piperazinyl-Pyridine Analogues | NEUROGEN CORPORATION | 2008-02-21 | — | — | US | disclosed |
| US-20080045525-A1 | Piperazinyl-Pyridine Analogues | NEUROGEN CORPORATION | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045525-A1 | Piperazinyl-Pyridine Analogues | PRLHR, GPR27, GPR68 | SGPL1 3491/4885ACACB 3803/4885ACACA 3724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.