⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30594560 | 0.77 | — | — | |
| SCHEMBL4903292 | 0.76 | — | — | |
| SCHEMBL4912143 | 0.75 | — | — | |
| SCHEMBL4917198 | 0.73 | L3MBTL1 (0.31) | — | |
| SCHEMBL4917203 | 0.73 | TAAR1 (0.31) | — | |
| SCHEMBL4553740 | 0.71 | CYP19A1 (0.41) | — | |
| SCHEMBL4912339 | 0.71 | POLB (0.35) | — | |
| Hydrochloric Acid SCHEMBL4433704 | 0.70 | CYP19A1 (0.41) | — | |
| SCHEMBL9299623 | 0.68 | KDM4E (0.42) | — | |
| SCHEMBL4953839 | 0.67 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108276339-A | Preparation method of 4, 5-diamino-1- (2-hydroxyethyl) pyrazole hydrochloride | 浙江鼎龙科技有限公司 | 2018-07-13 | — | — | CN | claimed |
| CN-105294564-B | A kind of synthetic method of 5 amino 1 (2 ethoxy) pyrazoles | 山东铂源药业有限公司 | 2018-01-23 | — | — | CN | claimed |
| US-7399317-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-07-15 | — | — | US | claimed |
| US-20070050922-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY | 2007-03-08 | — | — | US | claimed |
| CN-113135857-A | Synthesis method of N-hydroxyethyl-5-amino-1H pyrazole | 杭州迪克科技有限公司 | 2021-07-20 | — | — | CN | disclosed |
| CN-108276339-A | Preparation method of 4, 5-diamino-1- (2-hydroxyethyl) pyrazole hydrochloride | 浙江鼎龙科技有限公司 | 2018-07-13 | — | — | CN | disclosed |
| CN-105294564-B | A kind of synthetic method of 5 amino 1 (2 ethoxy) pyrazoles | 山东铂源药业有限公司 | 2018-01-23 | — | — | CN | disclosed |
| US-7399317-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-07-15 | — | — | US | disclosed |
| US-20080092306-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | GLENN ROBERT W JR | 2008-04-24 | — | — | US | disclosed |
| EP-1781241-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2007-05-09 | — | — | EP | disclosed |
| US-20070050922-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY | 2007-03-08 | — | — | US | disclosed |
| WO-2006026488-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-03-09 | — | — | WO | disclosed |