SCHEMBL4914912

SCHEMBL4914912

CCN(CC)c1ncnc(N(O)O)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
TSHR P16473 1/20 0.39
MAPT P10636 2/20 0.36
ALOX15 P16050 3/20 0.34
USP2 O75604 1/20 0.34
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 2/20 0.32
LMNA P02545 2/20 0.32
HTT P42858 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
SLC29A1 Q99808 1/20 0.32
ADORA2A P29274 1/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA9 Q16790 2/20 0.31
RAB9A P51151 1/20 0.31
CYP1A2 P05177 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL893013 0.89 TDP1 (0.46) TDP1TSHRMAPTALOX15USP2
SCHEMBL3868153 0.76 HSD17B10 (0.46) TSHRALOX15ALDH1A1LMNAHTT
SCHEMBL10444725 0.75 TDP1 (0.38) TDP1TSHRMAPTALOX15USP2
SCHEMBL1323657 0.75 TDP1 (0.45) TDP1TSHRMAPTALOX15KMT2A
SCHEMBL10879280 0.75 TDP1 (0.38) TDP1TSHRMAPTALOX15USP2
SCHEMBL5606801 0.75 MAPT (0.47) TDP1TSHRMAPTKMT2AALDH1A1
SCHEMBL11541977 0.75 TDP1 (0.38) TDP1TSHRMAPTALOX15USP2
SCHEMBL8383420 0.75 TDP1 (0.38) TDP1TSHRMAPTKMT2AMEN1
SCHEMBL9107350 0.75 TP53 (0.38) TDP1TSHRMAPTALOX15USP2
SCHEMBL9353787 0.73 TDP1 (0.41) TDP1TSHRALOX15KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080214810-A1 DYE-FORMING COUPLER, SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL, AND AZOMETHINE DYE COMPOUND UEHIRA SHIGEKI 2008-09-04 US disclosed
US-7365199-B2 Dye-forming coupler, silver halide photographic light-sensitive material, and azomethine dye compound FUJIFILM CORPORATION (JP) 2008-04-29 US disclosed
US-7196194-B2 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD (JP) 2007-03-27 US disclosed
US-20040122238-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD. 2004-06-24 US disclosed
US-20040096787-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD. 2004-05-20 US disclosed
US-6727053-B2 FORMS AN AZOMETHINE DYE UPON A COUPLING REACTION WITH AN OXIDIZED PRODUCT OF A DEVELOPING AGENT FUJI PHOTO FILM CO., LTD. (JP) 2004-04-27 US disclosed
US-20030091946-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and azomethine dye compound FUJIFILM CORPORATION (JP) 2003-05-15 US disclosed
US-20030073047-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJIFILM CORPORATION (JP) 2003-04-17 US disclosed
EP-1246006-A2 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD. (JP) 2002-10-02 EP disclosed
US-4393128-A MERCAPTO HETEROCYCLIC COMPOUND TO PREVENT SPOTS FUJI PHOTO FILM CO., LTD. (JP) 1983-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080214810-A1 DYE-FORMING COUPLER, SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL, AND AZOMETHINE DYE COMPOUND IK, CBR1, CNKSR1 TDP1 2795/4885TSHR 189/4885MAPT 3956/4885
US-20030073047-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound CBR1, IK, CBR3 TDP1 3199/4885TSHR 1024/4885MAPT 3337/4885
US-20040122238-A1 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound CBR1, CBR3, IK TDP1 3159/4885TSHR 799/4885MAPT 3572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.