SCHEMBL3868153

SCHEMBL3868153

CN(C)c1ncnc(N(O)O)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.46
CYP1A2 P05177 2/20 0.46
LMNA P02545 2/20 0.46
THRB P10828 1/20 0.46
BLM P54132 1/20 0.46
CREBBP Q92793 1/20 0.46
HPGD P15428 2/20 0.41
DYRK1A Q13627 1/20 0.35
ALDH1A1 P00352 5/20 0.34
KDM4E B2RXH2 2/20 0.34
ALOX15 P16050 1/20 0.34
POLB P06746 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
HTT P42858 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
GRM5 P41594 1/20 0.31
TSHR P16473 1/20 0.31
CYP2D6 P10635 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4914912 0.76 TDP1 (0.41) CYP1A2LMNAALDH1A1KDM4EALOX15
SCHEMBL2893718 0.73 HSD17B10 (0.41) HSD17B10CYP1A2LMNATHRBBLM
SCHEMBL9105174 0.73 TP53 (0.46) HSD17B10CYP1A2LMNATHRBBLM
SCHEMBL29581593 0.71 ALDH1A1 (0.47) HSD17B10CYP1A2LMNATHRBBLM
SCHEMBL2491794 0.71 ALDH1A1 (0.47) HSD17B10CYP1A2LMNATHRBBLM
SCHEMBL715925 0.71 HSD17B10 (0.39) HSD17B10CYP1A2LMNATHRBBLM
SCHEMBL10351402 0.71 HSD17B10 (0.39) HSD17B10CYP1A2LMNATHRBBLM
SCHEMBL8213611 0.71 HSD17B10 (0.39) HSD17B10CYP1A2LMNATHRBBLM
SCHEMBL28627551 0.71 HSD17B10 (0.39) HSD17B10CYP1A2LMNATHRBBLM
SCHEMBL3065404 0.69 ALDH1A1 (0.43) HSD17B10CYP1A2LMNATHRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1197799-B1 Silver halide photographic light-sensitive material comprising a yellow dye-forming coupler, and method for producing a yellow azomethine dye FUJIFILM CORP (JP) 2009-11-11 EP disclosed
US-7193080-B2 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM, CO., LTD. (JP) 2007-03-20 US disclosed
US-7009048-B2 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye FUJI PHOTO FILM CO., LTD. (JP) 2006-03-07 US disclosed
US-20050079456-A1 Dye-forming coupler and silver halide color photographic light-sensitive material FUJIFILM CORPORATION (JP) 2005-04-14 US disclosed
US-20050020821-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye FUJI PHOTO FILM CO., LTD. 2005-01-27 US disclosed
US-6803181-B2 USING A 1,3-DIKETOOXAZOLIDINE FUJI PHOTO FILM CO., LTD. (JP) 2004-10-12 US disclosed
US-6677110-B2 A DYE HAVING AN EXCELLENT HUE, STORAGE STABILITY, COLORFASTNESS, SHARPNESS AND LOW COST PRODUCTION DUE TO REDUCED STEPS FUJI PHOTO FILM CO., LTD. (JP) 2004-01-13 US disclosed
US-20030229230-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye FUJI PHOTO FILM CO., LTD. 2003-12-11 US disclosed
US-20030064332-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and azomethine dye compound FUJIFILM CORPORATION (JP) 2003-04-03 US disclosed
US-20020064736-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye FUJI PHOTO FILM CO., LTD. 2002-05-30 US disclosed
EP-1197799-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye Fuji Photo Film Co., Ltd. (JP) 2002-04-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020064736-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye CBR1, IK, CBR3 HSD17B10 2163/4885CYP1A2 170/4885LMNA 1985/4885
US-20030229230-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and method for producing an azomethine dye CBR1, IK, CBR3 HSD17B10 2163/4885CYP1A2 170/4885LMNA 1985/4885
US-20030064332-A1 Dye-forming coupler, silver halide photographic light-sensitive material, and azomethine dye compound CBR1, QDPR, IK HSD17B10 2564/4885CYP1A2 769/4885LMNA 1624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.