Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4914912 | 0.89 | TDP1 (0.41) | TDP1TSHRMAPTALOX15USP2 | |
| SCHEMBL1323657 | 0.84 | TDP1 (0.45) | TDP1TSHRMAPTALOX15SMN1; SMN2 | |
| SCHEMBL10444725 | 0.84 | TDP1 (0.38) | TDP1TSHRMAPTALOX15USP2 | |
| SCHEMBL5606801 | 0.84 | MAPT (0.47) | TDP1TSHRMAPTSMN1; SMN2KMT2A | |
| SCHEMBL11541977 | 0.84 | TDP1 (0.38) | TDP1TSHRMAPTALOX15USP2 | |
| SCHEMBL10879280 | 0.84 | TDP1 (0.38) | TDP1TSHRMAPTALOX15USP2 | |
| SCHEMBL9107350 | 0.84 | TP53 (0.38) | TDP1TSHRMAPTALOX15USP2 | |
| SCHEMBL1323774 | 0.81 | HTT (0.36) | TDP1TSHRMAPTALOX15SMN1; SMN2 | |
| SCHEMBL10344642 | 0.81 | TAAR1 (0.36) | TDP1TSHRMAPTSMN1; SMN2KMT2A | |
| SCHEMBL2741119 | 0.80 | TDP1 (0.64) | TDP1TSHRMAPTALOX15USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030120077-A1 | Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES PETER (US) | 2003-06-26 | — | — | US | claimed |
| US-6403681-B2 | STABILIZER FOR PLASTICS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-06-11 | — | — | US | claimed |
| US-20020058735-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES PETER (US) | 2002-05-16 | — | — | US | claimed |
| US-20020040145-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2002-04-04 | — | — | US | claimed |
| US-20010034449-A1 | Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-10-25 | — | — | US | claimed |
| US-20010031872-A1 | Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-10-18 | — | — | US | claimed |
| US-20010018520-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-08-30 | — | — | US | claimed |
| US-6271377-B1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-08-07 | — | — | US | claimed |
| US-6391949-B1 | — | — | None | — | — | US | disclosed |
| EP-2440524-A1 | STERICALLY HINDERED AMINE STABILIZERS | BASF SE (DE) | 2012-04-18 | — | — | EP | disclosed |
| US-20120083557-A1 | STERICALLY HINDERED AMINE STABILIZERS | BASF SE (DE) | 2012-04-05 | — | — | US | disclosed |
| WO-2010142572-A1 | STERICALLY HINDERED AMINE STABILIZERS | BASF SE (DE) | 2010-12-16 | — | — | WO | disclosed |
| US-6872832-B2 | Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-03-29 | — | — | US | disclosed |
| US-6586507-B2 | For stabilizing polyolefins, especially thermoplastic polyolefins, against the deleterious effects of oxidative, thermal and actinic radiation, also for stabilizing acid catalyzed and ambient cured coatings systems | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-01 | — | — | US | disclosed |
| US-20010034449-A1 | Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-10-25 | — | — | US | disclosed |
| US-20010031872-A1 | Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-10-18 | — | — | US | disclosed |
| US-20010020099-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-09-06 | — | — | US | disclosed |
| US-20010018520-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-08-30 | — | — | US | disclosed |
| US-20010016658-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-08-23 | — | — | US | disclosed |
| US-6271377-B1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020040145-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | TDP1 606/4885TSHR 4485/4885MAPT 324/4885 |
| US-20120083557-A1 | STERICALLY HINDERED AMINE STABILIZERS | AAAS, H1-5, H1-2 | TDP1 1032/4885TSHR 3145/4885MAPT 290/4885 |
| US-20020058735-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | OGG1, HAO2, POLH | TDP1 663/4885TSHR 4399/4885MAPT 423/4885 |
| US-20010016658-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | TDP1 606/4885TSHR 4485/4885MAPT 324/4885 |
| US-20010034449-A1 | Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | TDP1 606/4885TSHR 4485/4885MAPT 324/4885 |
| US-20010020099-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | TDP1 606/4885TSHR 4485/4885MAPT 324/4885 |
| US-20030120077-A1 | Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith | OGG1, POLH, OGFOD1 | TDP1 688/4885TSHR 4505/4885MAPT 430/4885 |
| US-20010018520-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | TDP1 606/4885TSHR 4485/4885MAPT 324/4885 |
| US-20010031872-A1 | Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | TDP1 606/4885TSHR 4485/4885MAPT 324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.