SCHEMBL491503

SCHEMBL491503

COc1ccc(Oc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 6/20 1.00
CA4 P22748 1/20 0.78
TSHR P16473 1/20 0.67
ALDH1A1 P00352 4/20 0.62
HTT P42858 3/20 0.62
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
MAPT P10636 1/20 0.62
CA12 O43570 1/20 0.61
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
CA7 P43166 1/20 0.61
CA9 Q16790 1/20 0.61
CA14 Q9ULX7 1/20 0.61
NR1H2 P55055 1/20 0.56
BAX Q07812 1/20 0.56
MAOA P21397 1/20 0.56
PGR P06401 2/20 0.56
TRPA1 O75762 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17283659 1.00 LTA4H (1.00) LTA4HCA4TSHRALDH1A1HTT
Phosphine SCHEMBL28324113 0.97 LTA4H (0.95) LTA4HCA4TSHRALDH1A1HTT
Diphenylether SCHEMBL818919 0.97 LTA4H (0.94) LTA4HCA4TSHRALDH1A1HTT
Diphenylether SCHEMBL28869227 0.97 LTA4H (0.94) LTA4HCA4TSHRALDH1A1HTT
Diphenylether SCHEMBL27827099 0.94 LTA4H (0.90) LTA4HCA4TSHRALDH1A1HTT
SCHEMBL15722134 0.93 LTA4H (0.86) LTA4HCA4TSHRALDH1A1HTT
SCHEMBL15834450 0.91 LTA4H (0.82) LTA4HCA4TSHRALDH1A1HTT
4-Phenoxyaniline SCHEMBL8216658 0.89 LTA4H (0.78) LTA4HCA4TSHRALDH1A1HTT
Anisole SCHEMBL29291357 0.89 LTA4H (0.78) LTA4HCA4TSHRALDH1A1HTT
SCHEMBL83811 0.88 CA1 (0.79) LTA4HCA4ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118515536-A Preparation process of low-cost p-phenoxy phenol 程冬冬 2024-08-20 CN claimed
CN-118084742-A New preparation method of Iguratimod intermediate 佳尔科生物科技南通有限公司 2024-05-28 CN claimed
JP-8325362-A None JP disclosed
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 US disclosed
US-12365655-B2 Compounds CTXT PTY LTD (AU) 2025-07-22 US disclosed
CN-112334466-B Compounds of formula (I) CTXT私人有限公司 2025-05-30 CN disclosed
CN-118970217-A Preparation method and application of aqueous zinc ion battery electrolyte additive, electrolyte and gel electrolyte 江苏师范大学 2024-11-15 CN disclosed
CN-118515536-A Preparation process of low-cost p-phenoxy phenol 程冬冬 2024-08-20 CN disclosed
CN-118271571-A Modified phenolic epoxy resin and preparation method thereof, conductive silver paste and preparation method thereof 深圳新宙邦科技股份有限公司 2024-07-02 CN disclosed
EP-4335439-A2 COMPOUNDS CTXT PTY LTD (AU) 2024-03-13 EP disclosed
CN-117645562-A Ligand for copper catalytic coupling reaction and application thereof 江西德璟生物科技有限公司 2024-03-05 CN disclosed
US-4386150-A CHROMAGENS HAVING A DYE MOIETY, A NITROGEN-NITROGEN MOIETY, AND A DIFFUSION-CONJTROLLING HYDROQUINONYL MOIETY; COLOR FILMS POLAROID CORPORATION (US) 1983-05-31 US disclosed
US-4355101-A PHOTOGRAPHIC DIFFUSION TRANSFER SYSTEMS POLAROID CORPORATION (US) 1982-10-19 US disclosed
US-4355092-A DIFFUSION TRANSFER PHOTOGRAPHIC FILM POLAROID CORPORATION (US) 1982-10-19 US disclosed
EP-0055858-A2 Photographic products, diffusion transfer photographic process, and compounds used therefor POLAROID CORPORATION (US) 1982-07-14 EP disclosed
US-4264507-A Novel xanthene dye developers POLAROID CORPORATION (US) 1981-04-28 US disclosed
US-4264704-A Novel xanthene dye developers POLAROID CORPORATION (US) 1981-04-28 US disclosed
US-4214968-A Ion-selective electrode EASTMAN KODAK COMPANY (US) 1980-07-29 US disclosed
US-4144025-A ORGANIC SOLVENT AND WATER POLAROID CORPORATION (US) 1979-03-13 US disclosed
US-4042603-A SUBSTITUTED DIBENZOFURAN OR 9-FLUORENONE FROM A DIPHENYL ETHER OR BENZOPHENONE UBE INDUSTRIES, LTD. (JA) 1977-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B LTA4H 4519/4885CA4 427/4885TSHR 832/4885
US-12365655-B2 Compounds SLC10A1, ABCB11, PCSK9 LTA4H 1822/4885CA4 183/4885TSHR 3583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.