Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 15/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | FPR2 | P25090 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4915419 | 0.89 | NPC1 (0.78) | CNR1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL4915664 | 0.85 | CNR1 (0.64) | CNR1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL22834260 | 0.84 | SMN1; SMN2 (1.00) | CNR1SMN1; SMN2LMNAMAPTEPHX2 | |
| SCHEMBL22834266 | 0.83 | CNR1 (1.00) | CNR1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL30417063 | 0.81 | SMN1; SMN2 (0.85) | CNR1SMN1; SMN2LMNAMAPTEPHX2 | |
| SCHEMBL21024443 | 0.80 | RAB9A (1.00) | SMN1; SMN2NPC1RAB9ALMNAMAPK1 | |
| SCHEMBL28648364 | 0.80 | RAB9A (1.00) | SMN1; SMN2NPC1RAB9ALMNAMAPK1 | |
| SCHEMBL3858644 | 0.80 | MCHR1 (0.79) | SMN1; SMN2NPC1RAB9ALMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL31072327 | 0.79 | RAB9A (0.97) | SMN1; SMN2NPC1RAB9ALMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL31072329 | 0.79 | RAB9A (0.97) | SMN1; SMN2NPC1RAB9ALMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120214808-A1 | Aryl Urea Derivatives for Treating Obesity | PROSIDION LIMITED (GB) | 2012-08-23 | — | — | US | claimed |
| US-20080261952-A1 | Aryl Urea Derivatives for Treating Obesity | PROSIDION LTD. (GB) | 2008-10-23 | — | — | US | claimed |
| US-20120214808-A1 | Aryl Urea Derivatives for Treating Obesity | PROSIDION LIMITED (GB) | 2012-08-23 | — | — | US | disclosed |
| US-20080261952-A1 | Aryl Urea Derivatives for Treating Obesity | PROSIDION LTD. (GB) | 2008-10-23 | — | — | US | disclosed |
| EP-1786422-A2 | ARYL UREA DERIVATIVES FOR TREATING OBESITY | Prosidion Limited (GB) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006018662-A2 | ARYL UREA DERIVATIVES FOR TREATING OBESITY | PROSIDION LIMITED (GB) | 2006-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261952-A1 | Aryl Urea Derivatives for Treating Obesity | CNR1, GPR119, UTS2R | CNR1 1/4885SMN1; SMN2 3931/4885NPC1 148/4885 |
| US-20120214808-A1 | Aryl Urea Derivatives for Treating Obesity | CNR1, GPR119, UTS2R | CNR1 1/4885SMN1; SMN2 3931/4885NPC1 148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.