Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25391946 | 0.85 | ALDH1A1 (0.35) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL4610205 | 0.85 | GAA (0.39) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL25395276 | 0.82 | CNR2 (0.37) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL1664069 | 0.82 | MEN1 (0.46) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL25394242 | 0.81 | HDAC8 (0.39) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL8266056 | 0.81 | KDM4E (0.42) | ALDH1A1KMT2AMAPTKDM4EHDAC6 | |
| SCHEMBL4474821 | 0.79 | KMT2A (0.43) | ALDH1A1KMT2AMEN1KDM4EHDAC6 | |
| SCHEMBL15030294 | 0.77 | KDM4E (0.42) | ALDH1A1KMT2AMAPTKDM4EHDAC6 | |
| SCHEMBL24709934 | 0.77 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1ALOX12KDM4E | |
| SCHEMBL17962565 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279848-A | Pan-JAKs inhibitor and application thereof | 四川海思科制药有限公司 | 2021-01-29 | — | — | CN | disclosed |
| US-20080146814-A1 | Process for producing N-protected boryl compounds | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146814-A1 | Process for producing N-protected boryl compounds | PBK, NME2, ZC3HAV1 | ALDH1A1 4082/4885KMT2A 2651/4885MEN1 741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.