SCHEMBL491544

SCHEMBL491544

C=C(C)C(=O)NCC(C)CC(C)O

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.35
RXFP1 Q9HBX9 1/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
KDM4E B2RXH2 1/20 0.30
POLB P06746 1/20 0.30
KISS1R Q969F8 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16097 0.84 TGFBR1 (0.39) TGFBR1RXFP1MEN1KMT2ATSHR
SCHEMBL12642676 0.84 TGFBR1 (0.39) TGFBR1RXFP1MEN1KMT2ATSHR
SCHEMBL4960192 0.82 TGFBR1 (0.38) TGFBR1RXFP1MEN1KMT2ATSHR
SCHEMBL799428 0.80 TGFBR1 (0.37) TGFBR1RXFP1MEN1KMT2ATSHR
SCHEMBL29518826 0.80 TGFBR1 (0.46) TGFBR1RXFP1MEN1KMT2ATSHR
SCHEMBL16939745 0.79 MTNR1A (0.38) TSHRALDH1A1CYP2D6CYP2C19KDM4E
SCHEMBL11586634 0.79 TGFBR1 (0.32) TGFBR1KISS1R
Propylene Glycol SCHEMBL28248623 0.78 TGFBR1 (0.44) TGFBR1RXFP1TSHRALDH1A1CYP2D6
SCHEMBL3738357 0.77 TGFBR1 (0.41) TGFBR1RXFP1TSHRALDH1A1CYP2D6
SCHEMBL97375 0.77 TGFBR1 (0.41) TGFBR1RXFP1TSHRALDH1A1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8105670-B2 Glycoluril resin and polyol resin dual members XEROX CORPORATION (US) 2012-01-31 US disclosed
EP-2237115-A1 Intermediate transfer member comprising a coating of a mxiture of glycoluril resin and polyol resin Xerox Corporation (US) 2010-10-06 EP disclosed
US-20100248108-A1 GLYCOLURIL RESIN AND POLYOL RESIN DUAL MEMBERS XEROX CORPORATION (US) 2010-09-30 US disclosed