Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 7/20 | 0.58 |
| ▸ | HTR3A | P46098 | 4/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL260649 | 0.94 | CHRNA7 (0.64) | CHRNA7HTR3AKCNH2HTR3EHTR3B | |
| SCHEMBL261359 | 0.94 | CHRNA7 (0.64) | CHRNA7HTR3AKCNH2HTR3EHTR3B | |
| SCHEMBL261361 | 0.94 | CHRNA7 (0.64) | CHRNA7HTR3AKCNH2HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL492406 | 0.93 | CHRNA7 (0.63) | CHRNA7HTR3AKCNH2HTR3EHTR3B | |
| SCHEMBL12713921 | 0.85 | CHRNA7 (0.43) | CHRNA7HTR3AKCNH2 | |
| SCHEMBL12713951 | 0.85 | CHRNA7 (0.43) | CHRNA7HTR3AKCNH2 | |
| SCHEMBL492009 | 0.82 | HTR3A (0.51) | CHRNA7HTR3AKCNH2HTR3EHTR3B | |
| SCHEMBL492869 | 0.82 | HTR3A (0.51) | CHRNA7HTR3AKCNH2HTR3EHTR3B | |
| SCHEMBL12678110 | 0.81 | CHRNA7 (0.53) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL4875566 | 0.79 | CHRNA7 (0.56) | CHRNA7HTR3AHTR3EHTR3BHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080154037-A1 | INDAZOLES, BENZOTHIAZOLES, AND BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF | XIE WENGE | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080154037-A1 | INDAZOLES, BENZOTHIAZOLES, AND BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF | CHRNA7, CHRNA5, CHRNA3 | CHRNA7 1/4885HTR3A 152/4885KCNH2 331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.