SCHEMBL4915532

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4911322	0.89	NPC1 (0.59)	MAPTTRPV1MEN1KMT2ANPC1
	SCHEMBL5176441	0.89	MAPT (0.56)	MAPTTRPV1MEN1KMT2ANPC1
	SCHEMBL4123352	0.84	MAPT (0.82)	MAPTNPC1RAB9ACNR1DNMT3B
	SCHEMBL4921357	0.84	MAPT (0.82)	MAPTRAB9ACNR1DNMT3BLMNA
	SCHEMBL4912509	0.82	MAPT (1.00)	MAPTCNR1
	SCHEMBL4922831	0.82	MAPT (0.79)	MAPTKMT2ANPC1RAB9ASMN1; SMN2
	Hydrochloric Acid SCHEMBL4915559	0.81	MAPT (0.98)	MAPTCNR1
	SCHEMBL4118606	0.81	MAPT (0.76)	MAPTMEN1KMT2ANPC1RAB9A
	SCHEMBL4119185	0.79	MAPT (0.70)	MAPTMEN1KMT2ASMN1; SMN2CNR1
	SCHEMBL5175995	0.79	MEN1 (0.59)	MAPTTRPV1MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.