Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 3/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4910276 | 0.91 | GSTO1 (0.37) | KMT2AHTTPPARDCA1CA2 | |
| SCHEMBL4920245 | 0.81 | ALDH1A1 (0.35) | KMT2AHTTLMNAPOLBALDH1A1 | |
| SCHEMBL1471222 | 0.78 | KMT2A (0.41) | KMT2APPARDCA1CA2ACHE | |
| SCHEMBL4916166 | 0.78 | CA1 (0.43) | KMT2APPARDCA1CA2ACHE | |
| SCHEMBL4740697 | 0.78 | KMT2A (0.41) | KMT2APPARDCA1CA2ACHE | |
| SCHEMBL1470495 | 0.78 | KMT2A (0.41) | KMT2APPARDCA1CA2ACHE | |
| SCHEMBL14538800 | 0.77 | KMT2A (0.39) | KMT2APPARDCA1CA2ACHE | |
| SCHEMBL4912719 | 0.75 | PPARG (0.45) | PPARDLMNAMAPTCYP1A2 | |
| SCHEMBL4013407 | 0.72 | KMT2A (0.44) | KMT2AHTTCA1CA2ACHE | |
| SCHEMBL30967925 | 0.72 | KMT2A (0.44) | KMT2AHTTCA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287477-A1 | Novel Compounds as Modulators of Ppar | KALYPSYS, INC. (US) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287477-A1 | Novel Compounds as Modulators of Ppar | PPARG, PPARA, PPARD | KMT2A 4143/4885HTT 2813/4885PPARD 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.