SCHEMBL491580

SCHEMBL491580

C=Cc1cc(F)ccc1F

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 8/20 0.54
CES2 O00748 3/20 0.43
CES1 P23141 3/20 0.43
CA3 P07451 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
ALDH1A1 P00352 1/20 0.37
ERN1 O75460 1/20 0.35
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2A Q12879 1/20 0.34
GRIN2B Q13224 1/20 0.34
GRIN2C Q14957 1/20 0.34
GRIN3A Q8TCU5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29442889 1.00 NFE2L2 (0.54) NFE2L2CES2CES1CA3CA6
SCHEMBL3251725 0.81 NFE2L2 (0.50) NFE2L2CES2CES1CA3CA6
SCHEMBL16962237 0.80 NFE2L2 (0.54) NFE2L2CES2CES1CA3CA6
SCHEMBL319771 0.80 NFE2L2 (0.54) NFE2L2CES2CES1CA3CA6
SCHEMBL29413981 0.80 NFE2L2 (0.54) NFE2L2CES2CES1CA3CA6
SCHEMBL5252638 0.79 NFE2L2 (0.58) NFE2L2CES2CES1CA3CA6
SCHEMBL25287952 0.78 NFE2L2 (0.38) NFE2L2CES2CES1CA3CA6
SCHEMBL16961910 0.78 NFE2L2 (0.39) NFE2L2ALDH1A1ERN1
SCHEMBL29700768 0.78 NFE2L2 (0.39) NFE2L2ALDH1A1ERN1
SCHEMBL19798041 0.76 ESR2 (0.45) NFE2L2CA3CA6CA5ACA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 529 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116948245-A Foam matrix material for vertical-surface plant planting and preparation method thereof 丽水市润生苔藓科技有限公司 2023-10-27 CN claimed
CN-112500513-B Preparation system and process of alpha olefin-fluorostyrene polymer 南京延长反应技术研究院有限公司 2022-12-16 CN claimed
CN-113136001-B Preparation method of ethylene-fluorostyrene copolymer 中国科学院长春应用化学研究所 2022-05-06 CN claimed
CN-113136001-A Preparation method of ethylene-fluorostyrene copolymer 中国科学院长春应用化学研究所 2021-07-20 CN claimed
CN-112500513-A Preparation system and process of alpha olefin-fluorostyrene polymer 南京延长反应技术研究院有限公司 2021-03-16 CN claimed
CN-107722155-B Alpha olefin-fluorostyrene polymer and preparation method thereof 中国科学院长春应用化学研究所 2021-01-08 CN claimed
CN-107722155-A A kind of alhpa olefin fluorobenzene ethene polymer and preparation method thereof 中国科学院长春应用化学研究所 2018-02-23 CN claimed
EP-2297107-B1 [4-(1-AMINO-ETHYL) -CYCLOHEXYL]-METHYL-AMINE AND [6-(1-AMINO-ETHYL) -TETRAHYDRO- PYRAN-3-YL]-METHYL-AMINE DERIVATIVES AS ANTIBACTERIALS ACTELION PHARMACEUTICALS LTD (CH) 2013-11-13 EP claimed
US-8349829-B2 [4-(1-amino-ethyl)-cyclohexyl]-methyl-amine and [6-(1-amino-ethyl)-tetrahydro-pyran-3-yl]-methyl-amine derivatives as antibacterials ACTELION PHARMACEUTICALS LTD. (CH) 2013-01-08 US claimed
US-20110082132-A1 [4-(1-AMINO-EHTYL) - CYCLOHEXYL] -METHYL-AMINE AND [6-(1-AMINO-EHTYL) -TETRAHYDRO-PYRAN-3-YL] -METHYL-AMINE DERIVATIVES AS ANTIBACTERIALS ACTELION PHARMACEUTICALS LTD. (CH) 2011-04-07 US claimed
EP-2297107-A1 Ý4-(1-AMINO-ETHYL) -CYCLOHEXYL¨-METHYL-AMINE AND Ý6-(1-AMINO-ETHYL) -TETRAHYDRO- PYRAN-3-YL¨-METHYL-AMINE DERIVATIVES AS ANTIBACTERIALS Actelion Pharmaceuticals Ltd. (CH) 2011-03-23 EP claimed
WO-2009147616-A1 [4-(1-AMINO-ETHYL) -CYCLOHEXYL] -METHYL-AMINE AND [6-(1-AMINO-ETHYL) -TETRAHYDRO- PYRAN-3-YL] -METHYL-AMINE DERIVATIVES AS ANTIBACTERIALS ACTELION PHARMACEUTICALS LTD (CH) 2009-12-10 WO claimed
US-20090131444-A1 Aminopiperidine Quinolines and Their Azaisosteric Analogues with Antibacterial Activity ASTRAZENECA AB (SE) 2009-05-21 US claimed
US-7141177-B2 Etching method and composition for forming etching protective layer AZ ELECTRONIC MATERIALS USA CORP. (US) 2006-11-28 US claimed
US-6806019-B2 COATING SUBSTRATES WITH PHOTORESIST MIXTURES COMPRISING NOVOLAKS, ACRYLIC ESTER COPOLYMERS AND PHOTOSENSITIZERS, THEN EXPOSING THE COATINGS AND DEVELOPING, TO FORM SEMICONDUCTORS OR FLAT PANEL DISPLAYS CLARIANT FINANCE (BVI) LIMITED (VG) 2004-10-19 US claimed
US-20040170917-A1 Method of forming thick resist pattern AZ ELECTRONIC MATERIALS USA CORP. 2004-09-02 US claimed
EP-0092794-B2 LIGHT-SENSITIVE PRINTING PLATE FUJI PHOTO FILM CO., LTD. (JP) 1992-04-08 EP claimed
EP-0092794-B1 LIGHT-SENSITIVE PRINTING PLATE FUJI PHOTO FILM CO., LTD. (JP) 1987-07-15 EP claimed
US-4557994-A MICROPATTERN OF TERPOLYMER RESISTANT TO RUBBING AND PRESSURE FUJI PHOTO FILM CO., LTD. (JP) 1985-12-10 US claimed
EP-0092794-A2 Light-sensitive printing plate FUJI PHOTO FILM CO., LTD. (JP) 1983-11-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110082132-A1 [4-(1-AMINO-EHTYL) - CYCLOHEXYL] -METHYL-AMINE AND [6-(1-AMINO-EHTYL) -TETRAHYDRO-PYRAN-3-YL] -METHYL-AMINE DERIVATIVES AS ANTIBACTERIALS DOT1L, EHMT1, Q6ZSR9 NFE2L2 1629/4885CES2 2211/4885CES1 1973/4885
US-20090131444-A1 Aminopiperidine Quinolines and Their Azaisosteric Analogues with Antibacterial Activity AAAS, AMPD2, AMPD3 NFE2L2 2298/4885CES2 2994/4885CES1 4369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.